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商品描述
Serineprotease22,alsoknownasBrain-specificserineprotease4(BSSP-4)ortryptaseepsilon,isaserineprotease,whichpreferentiallycleavesthesyntheticsubstrateH-D-Leu-Thr-Arg-pNAcomparedtotosyl-Gly-Pro-Arg-pNA.BSSP-4isexpressedabundantlyintheepithelialcellsoftheairways,includingtrachea,esophagusandfetallung,butscarceinadultlungandexpressedatlowlevelsinplacenta,pancreas,prostateandthyroidgland.BSSP-4belongstothepeptidaseS1familyandrelatedtotrypsin,referentiallyhydrolyzingsubstratesafterarginineandlysineresidues.However,BSSP-4islesssusceptIBLetoinhibitionbycommontrypsininhibitorssuchasaprotinin,α1-antitrypsinandsecretoryleukocyteproteaseinhibitor.BSSP-4efficientlyconvertspro-urokinase-typeplasminogenactivatortoitsmature,activeform.
| Source | HEK293 |
| Names | Brain-SpecificSerineProtease4,BSSP-4,SerineProtease22,SerineProtease26,TryptaseEpsilon,PRSS22,BSSP4,PRSS26 |
| Accession# | Q9GZN4 |
| Formulation | Suppliedasa0.2μMfilteredsolutionof20mMHAc-NaAc,150mMNaCl,10%Glycerol,pH4.5 |
| Shipping | Theproductisshippedondryice/icepacks. |
| Storage | Storeat<-20°C,stablefor6monthsafterreceipt. Pleaseminimizefreeze-thawcycles. |
| Purity | Greaterthan95%asdeterminedbySEC-HPLCandreducingSDS-PAGE. |
| Endotoxin | Lessthan0.1ng/μg(1IEU/μg). |
| AminoAcidSequence | ARIPVPPACGKPQQLNRVVGGEDSTDSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLGNPGSRSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCWISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERDACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRGRAQGGGALRAPSQGSGAAARSHHHHHH |
