Clone
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BN-1
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Size
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100μg/vial
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Form
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lyophilized
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Ig type
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mouse IgG2b
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Specificity
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No cross reactivity with other proteins.
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Species
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Human, mouse, rat
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Immunogen
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Recombinant polypeptide containing amino acids 189-398 of human Bin1.
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Contents
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Mouseascitesfluid,1.2%sodiumacetate,2mgBSA,with0.01mgNaN3as
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preservative.
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Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be100μg/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can alsobe aliquotted and stored frozenat -20˚C for a longer time.Avoid repeated freezing and thawing.
1. Sakamuro, D.; Elliott, K. J.; Wechsler-Reya, R.; Prendergast, G. C. : BIN1 is a novel MYC-interacting protein with features of a tumour suppressor. Nature Genet. 14: 69-77, 1996.
2. Negorev, D.; Riethman, H.; Wechsler-Reya, R.; Sakamuro, D.; Prendergast, G. C.; Simon, D. : The Bin1 gene localizes to human chromosome 2q14 by PCR analysis of somatic cell hybrids and fluorescence in situ hybridization. Genomics 33: 329-331, 1996.
3. Nicot, A.-S.; Toussaiant, A.; Tosch, V.; Kretz, C.; Wallgren-Petterson, C.; Iwarsson, E.; Kingston, H.; Garnier, J.-M.; Biancalana, V.; Oldfors, A.; Mandel, J.-L.; Laporte, J. : Mutations in amphiphysin 2 (BIN1) disrupt interaction with dynamin 2 and cause autosomal recessive centronuclear myopathy. (Letter) Nature Genet. 39: 1134-1139, 2007.
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