MW:80,000
Lyophilizedfrom20mMphosphate,pH7.4,with150mMNaCl
Storage:-20°C
BuyTransferrin,CynomolgusMonkeyPlasmadirectfromthemanufacturer.Samedayshippingforthislaboratoryreagent.($85.00/1mg)
Purity:>=95%bySDS-PAGE
CountryofOrigin:MonkeyplasmawasobtainedfromhealthyanimalsofUSoriginandunderthecareofaregisteredveterinarian.
PreparedfromdonormonkeysthathavebeenindividuallytestedforB-Virus(HerpesVirusSimiae)andfoundtobenegative
AthensResearch&TechnologyproductsarelaboratoryreagentsandarenottobeadmiNISTeredtohumansorusedforanydrugpurpose.Forresearchuseonly.
Forresearchuseorforuseinfurthermanufacturing.
Myeloperoxidase Enzyme Immunoassay Kit
髓过氧化物酶
免疫分析试剂盒
Human MPO EIA KIT FEATURES:
USE - Measure human MPO in a variety of
matrices
SAMPLE -Serum, Platelet-Poor Heparin Plasma, Saliva, Urine or Tissue Culture
Media
SAMPLES / KIT - 40 in duplicate
SENSITIVITY - 0.068 ng/mL
STABILITY - liquid reagents stable at 4°C
QUICK RESULTS - 2.5 HOURS
Myeloperoxidase (MPO) is a tetrameric
heme-containing protein abundantly produced in neutrophil granulocytes where it
plays an important anti-microbial role. During degranulation MPO is released
into the extracellular space. There, as part of the neutrophils “respiratory
burst”, it produces hypochlorous acid from hydrogen peroxide and Cl–. MPO also
uses hydrogen peroxide to oxidize tyrosine to the tyrosyl radical. Both
hypochlorous acid and tyrosyl are cytotoxic and when present can kill bacteria
and other pathogens. Hereditary deficiency of myeloperoxidase predisposes
individuals to immune deficiency.
Studies have shown an association between
elevated MPO levels and coronary artery disease, and in 2003 it was suggested
that MPO may serve as a sensitive predictor of myocardial infarction in
patients complaining of chest pain. Since that time the clinical utility of MPO
testing in cardiac patients has been solidly established in the literature with
well over 100 papers published. In 2010 this clinical application was further
refined by additional studies which determined that measuring both MPO and
C-reactive protein (CRP) provided more accurate prediction of mortality risk
than measuring just CRP alone.