- 转铁蛋白和apotranferrins
- Lab Reagents: Smart Buffers and Reagents
- 分子生物学用酶：分子生物学用酶
- 蛋白质纯化：阿波罗20毫升超滤
- 免疫球蛋白
- qPCR：基因分析和基因面板
- PCR : PCR Products
- 牛奶和血小板蛋白
- DNA & RNA Sequencing : Dye Terminator clean-up
- Aptamers: Catalogue Aptamers
- Peptide Synthesis : Amino Acids
- 运输和其他蛋白质
- DNA: Whole DNA
- STEM学习：STEM工具包
- 低内毒素水平蛋白质
- 提取和纯化-RNA：组织/培养
- 转染-EZ生物系统：细胞系
- 凝血因子
- 分析试剂盒
- 抗体
- Gel Electrophoresis: Gel Electrophoresis
Aptamers: Catalogue Aptamers
Please remember to pick your Modification from "Related items"
If the listed modifications do not meet your needs many other modifications are available on request
All Aptamers from Base Pair Bio are available with the following modifications
Please choose your modification and add as an extra catalogue number:
ATWUNMOD - Unmodified
ATWAMINE - Amine modification
ATWBIOTIN - Biotin modification
ATWTHIOL - Thiol modification (extra charge)
ATWFLUOR - Fluor (all) modification (extra charge)
Interleukin 6 (IL6) Aptamer to Murine Protein Target
IL6 (mu) - sandwich pair ATW0077
Base Pair Bio
| Catalogue No. | Description | Pack Size | Price | Qty |
|
|---|---|---|---|---|---|
| ATW0077-100 | IL6 (mu) | 10 AEU (100ug) | POA | Quantity | Add to Order |
| ATW0077-25 | IL6 (mu) | 2.5 AEU (25ug) | POA | Quantity | Add to Order |
Related products
Interleukin 6 (IL6) Aptamer to Murine Protein Target
IL6 (mu) - sandwich pair ATW0077
Base Pair Bio
Interleukin 6 (IL6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. It is secreted by T cells and macrophages to stimulate immune response and is also considered a "myokine," a cytokine produced from muscle, and is elevated in response to muscle contraction. It is significantly elevated with exercise, and precedes the appearance of other cytokines in the circulation. During exercise, it is thought to act in a hormone-like manner to mobilize extracellular substrates and/or augment substrate delivery. Additionally, osteoblasts secrete IL6 to stimulate osteoclast formation. Smooth muscle cells in the tunica media of many blood vessels also produce IL6 as a pro-inflammatory cytokine. IL6"s role as an anti-inflammatory cytokine is mediated through its inhibitory effects on TNF-alpha and IL1, and activation of IL1ra and IL10.
Target: IL-6 (Interleukin-6)
Target Species: murine
Target Type: protein
Affinity Constant (Kd): 5.4 nM
Default 3" Linker (Spacer) is 10T. Please submit a custom quote request for other options.
This aptamer was selected by scientists at Base Pair Biotechnologies using proprietary methods, recombinant Murine Interleukin 6, [BioLegend Cat# 575706] and 1X PBS, pH = 7.4. ATW0077is a sandwich pair with ATW0082 and ATW0083.Let us know if you have any questions about its development or potential uses.
Aptamer informationKd 7.4 ± 1.7 nM
IL6 ATW0077.ATW0082 #EALRN#D92GX datasheet
IL6 ATW0077.ATW0083 #EALRN#D95W1 datasheet
Please choose your modification and add as an extra catalogue number:ATWUNMOD - UnmodifiedATWAMINE - Amine modificationATWBIOTIN - Biotin modificationATWTHIOL - Thiol modification (extra charge)ATWFLUOR - Fluor (all) modification (extra charge)
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
Interleukin 6 (IL6) Aptamer to Murine Protein Target
IL6 (mu) - sandwich pair ATW0077
Base Pair Bio
Antibody Equivalent Units (AEU). There is a large molecular weight difference in antibodies (typically 150,000 Da) and Base Pair’s aptamers (~14,000 Da). We provide our aptamers in terms of moles, where the aptamer moles in 1 AEU is equal to antibody moles in the typical 100 microgram shipment from a leading antibody vendor. Therefore our standard 2.5 AEU (25ug) or 5 AEU (50ug) delivery is 2.5 and 5 times the equivalent moles of a standard antibody delivery of 100 microgram respectively.
If you cannot find the answer to your problem below then please contact us or telephone 01954 210 200
