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蚂蚁淘在线 / 品牌中心 / Biosensis / Biosensis/Mouse monoclonal antibody to human Sodium channel protein type 8 subunit alpha [4G7]: IgG/M-864-100/100 µg
商品描述
| Description | Sodiumchannelproteintype8subunitalphamediatesthevoltage-dependentsodiumionpermeABIlityofexcitablemembranes.Adoptingopenedorclosedconformationinresponsetothevoltagedifferenceacrossthemembrane,theproteinformsasodium-selectivechannelthroughwhichNaionsmaypassinaccordancewiththeirelectRochemicalgrADIent.Itisamulti-passtransmembraneproteinthatiswidelyexpressedinneuronsofthecentralandperipheralnervoussystem.Therearefournamedisoforms.Thesequencecontains4internalrepeats,eachwith5hydrophobicsegments(S1,S2,S3,S5,S6)andonepositivelychargedsegment,S4. SegmentsS4arethoughttobethevoltage-sensorsandarecharacterisedbyaseriesofpositivelychargedaminoacidsateverythirdposition. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µg |
| Antigen | PartialrecombinanthumanSodiumchannelproteintype8subunitalpha(aminoacids1854-1951)withaGSTtag. |
| Clone | 4G7 |
| OtherNames | SodiumchannelproteintypeVIIIsubunitalpha;Voltage-gatedsodiumchannelsubunitalphaNav1.6;SCN8A;MED |
| Accession | SCN8A_HUMAN |
| Producedin | Mouse |
| Purity | ProteinGpurifiedimmunoglobulin |
| Applications | ThisantibodyisrecommendedforWB,immunofluorescenceanddirectELISA.Therecommendeddilutionforthisantibodyis10µg/mlforimmunofluorescence.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | SpecificityhasbeenconfirmedbyWBanddirectELISAagainsttheantigen. |
| Cross-reactivity | Human,mouseandrat.Otherspecieshavenotbeentested. |
| Blastit | Toseethesharedidentitybetweendifferentspeciesorotherproteins,followthelinkintheAccessionfield,selectthesequencethatyouareinterestedinandcopyandpasteitHEREandblast/formatit. |
| Form | LyophilisedfromPBSpH7.2 |
| Reconstitution | Reconstitutein100µlofsterilewater.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitutionkeepaliquotsat-20ºCforhigherstabilityorat4ºCwithanappropriateantibacterialagent.Glycerol(1:1)maybeaddedforadditionalstability.Avoidrepetitivefreeze/thawcycles. |
| ExpiryDate | 12monthsafterpurchase |
