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蚂蚁淘在线 / 品牌中心 / Biosensis / Biosensis/Rabbit polyclonal antibody to human C-reactive protein (209-224): Affinity purified/R-1047-100/100 µg
商品描述
| Description | C-reactiveproteinhasseveralrolesassociatedwithhostdefencesuchas;promotingagglutination,bacterialcapsularswelling,phagocytosisandcomplementfixationthroughitscalcium-dependentbindingtophosphorylcholine.ItcaninteractwithDNAandhistonesandmayscavengenuclearmaterialreleasedfromdamagedcirculatingcells.COFACTOR:Binds2calciumionspersubunit.C-reactiveproteinexistsasahomopentamer.Thereare2alternativelysplicedisoforms.C-reactiveproteinisfoundinplasmaanditsconcentrationincreasesgreatlyduringacutephaseresponsetotissueinjury,infectionorotherinflammatorystimuli.ItisinducedbyIL-1andIL-6. |
| BatchNo. | Seeproductlabel |
| Unitsize | 100µg |
| Antigen | Asyntheticpeptidecorrespondingtoaregion(209-224aa)fromhumanC-reactiveprotein.Toenhancetheimmunologicalresponse,thispeptidewascoupledtocarrierproteinBSA. |
| OtherNames | CRP;PTX1; |
| Accession | P02741CRP_HUMAN; |
| Producedin | Rabbit |
| Purity | Affinitypurifiedonantigencolumn |
| Applications | WesternBlotting(WB).Aconcentrationof1.0µg/mlisrecommendedforWB.HumanC-reactiveprotein(isoform1)hasapredictedlengthof224residuesandMWof25kDa.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser. |
| Specificity | ThespecificityofthisantibodyhasbeenconfirmedbyWBagainsttheantigen. |
| Cross-reactivity | Human; |
| Blastit | Ifyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechosecarefully,asthesequenceyouchosemaybeaprecursorratherthanthematureproteinforexample. |
| Form | Lyophilisedwith5mgBSA,0.9mgNaCl,0.2mgNa2HPO4,0.05mgThimerosal,0.05mgNaN3 |
| Reconstitution | Reconstitutein100µlofsteriledistilledwatertoachieveanantibodyconcentrationof1mg/ml.Centrifugetoremoveanyinsolublematerial. |
| Storage | Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles. |
| ExpiryDate | 12monthsafterpurchase |
