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Biosensis/Mouse monoclonal antibody to Glucagon [IMD-7]: IgG/M-1158-100/100 µg

价格
¥6540.00
货号:M-1158-100
浏览量:127
品牌:Biosensis
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全国联保
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商品描述
DescriptionTheglucagonpreproproteiniscleavedintoanumberofdistinctpeptidesthatincludeglucagon,glucagon-likepeptide1(GLP-1)andglucagon-likepeptide2(GLP-2).Glucagonhasakeyroleinglucosemetabolismandhomeostasis.Thereleaseofglucagonisstimulatedbyhypoglycemiaandregulatesthelevelofbloodglucosebyincreasinggluconeogenesisanddecreasingglycolysis.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenPolymerizedporcineglucagon
CloneIMD-7
OtherNamesGLP1;GLP2;GRPP;GCG;
AccessionP01274GLUC_PIG;P01275GLUC_HUMAN;
ProducedinMouse
PurityIgG
ApplicationsImmunohistochemistry(IHC).Aconcentrationof1.0-2.0µg/mlisrecommendedtodetecttheproteininformalinfixedandparaffinembeddedtissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyIHCagainsttheantigen.
Cross-reactivityHuman;rat;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3
ReconstitutionReconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAfterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles
ExpiryDate12monthsafterpurchase