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Biosensis/Mouse monoclonal antibody to Cyclin-dependent kinase 7 [IMD-26]: IgG/M-1175-100/100 µg

价格
¥6540.00
货号:M-1175-100
浏览量:119
品牌:Biosensis
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商品描述
DescriptionCyclin-dependentkinase7(CDK7)belongstothecyclin-dependentproteinkinasefamily.CDK7associateswithcyclinHandMAT1toformthetrimericCDK-activatingkinase(CAK)complex.CAKactivatescyclin-associatedkinasessuchasCDK4andCDK6bythreoninephosphorylation.
BatchNo.Seeproductlabel
Unitsize100µg
AntigenRecombinanthumanCyclin-dependentkinase7(CDK7)
CloneIMD-26
OtherNamesCelldivisionproteinkinase7;CDK-activatingkinase;CAK;CAK1;TFIIHbasaltranscriptionfactorcomplexkinasesubunit;39kDaproteinkinase;P39Mo15;STK1;CDK7;MO15;CDKN7;SerinethreoninekinaseStk1;
AccessionP50613CDK7_HUMAN;
ProducedinMouse
PurityIgG
ApplicationsImmunohistochemistry(IHC)andWesternBlotting(WB).Aconcentrationof0.25µg/mlisrecommendedforWB.HumanCDK7hasapredictedlengthof346residuesandMWof39kDa.Aconcentrationof0.5µg/mlisrecommendedtodetecttheproteininformalin/acetonefixedfrozentissues.Biosensisrecommendsoptimaldilutions/concentrationsshouldbedeterminedbytheenduser.
SpecificityThespecificityofthisantibodyhasbeenconfirmedbyWBandIHCagainsttheantigen.
Cross-reactivityHuman;
BlastitIfyouwishtousethisproductinaspeciesotherthanthosespecifiedhereandwanttodeterminetheaminoacidsequencehomologybetweentheimmunogenandthecorrespondingproteininthatspecies,simplycopytheaminoacidsequenceforthisimmunogenandtestitontheBLASTdatabasethatyoucanaccessthroughthelinkbelow.Pleasenotethatantibodiesraisedagainstsyntheticpeptidesarequiteoftenveryspecificforthatpeptide.Whatthismeansinpractiseisthatasingleaminoaciddifferencemaybeenoughtorestrictthespecificitytoaparticularmolecule.TheBLASTdatabasecanalsobeusedtocompareanyaminoacidsequencebetweenspeciesandbetweenprotein.ThefullaminoacidsequenceofthetargetproteincanbefoundbyfollowingthelinkintheAccessionfield.YoucanthensearchanyaminoacidsequenceinthetargetproteinusingtheBLASTdatabase.Whenselectingasequencetosearch,pleasechoosecarefully,asthesequenceyouchoosemaybeaprecursorratherthanthematureproteinforexample.
FormLyophilizedfrom1.2%sodiumacetate,2mgBSA,0.01mgNaN3
ReconstitutionReconstitutein1mlofPBS(pH7.4)toachieveanantibodyconcentrationof100µg/ml.Centrifugetoremoveanyinsolublematerial.
StorageAtleast12monthsafterpurchaseat2-4°C(lyophilizedformulations).Afterreconstitution,aliquotandstoreat-20°CforahigherstABIlity.Avoidfreeze-thawcycles
ExpiryDate12monthsafterpurchase