Description

CD45.2 is an alloantigen of CD45, expressed by Ly5.2 bearing mouse strains (e.g., A, AKR, BALB/c, CBA/Ca, CBA/J, C3H/He, C57BL, C57BR, C57L, C58, DBA/1, DBA/2, NZB, SWR, 129). CD45, a member of the protein tyrosine phosphatase (PTP) family, is a 180-240 kD glycoprotein expressed on all hematopoietic cells except mature erythrocytes and platelets. There are multiple isoforms in the mouse that play key roles in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation states of the cell as well as specific cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

Product Details  Biolegend揭示出对神经系统以及影响神经系统的疾病的更好理解的研究可以转化为改善数百万生命的治疗方法。BioLegend提供广泛的产品组合，为您的神经科学实验提供解决方案，包括抗体，免疫测定溶液，重组蛋白，磁性细胞分离和单细胞蛋白质组学试剂。我们的试剂是与该领域的杰出领导者（如迈克尔·J·福克斯基金会）合作建造的（请参见下面的“产品亮点”标签），这表明我们承诺与您的团队合作寻找新发现，为我们的客户带来新的选择和全面的解决方案研究神经系统疾病的解决方案。