Cytokines are small soluble glycoproteins that act as extracellular signaling molecuels and meidate communications between cells. They regulate immunity, inflammation and hematopoiesis as well as cell growth, migration, development and differentiation. Cytokines act in large tightly regulated networks where both the production and action of one cytokine is affected by the behavior of other cytokines. The accurate measurement of the expression profile of cytokines in a sample is critical to complete and in-depth understanding of disease progression and immune responses.The LEGENDplex™ Mouse Inflammation Panel is a multiplex assay by using fluorescence–encoded beads suitable for the analysis on various flow cytometers. This panel allows simultaneous quantification of 13 mouse cytokines, including IL-1α, IL-1β, IL-6, IL-10, IL-12p70, IL-17A, IL-23, IL-27, MCP-1, IFN-β, IFN-γ, TNF-α, and GM-CSF. Most of cytokines in this panel are produced by innate immune cells, linking the innate and adaptive immunity and/or bystander cells. This assay panel provides higher detection sensitivities and broader dynamic ranges than traditional ELISA methods. The panel has been validated by detecting expected changes in biological samples.A LEGENDplex™ Mix and Match system is available to customize assays for specificities within this panel.
Product Details Biolegend揭示出对神经系统以及影响神经系统的疾病的更好理解的研究可以转化为改善数百万生命的治疗方法。BioLegend提供广泛的产品组合，为您的神经科学实验提供解决方案，包括抗体，免疫测定溶液，重组蛋白，磁性细胞分离和单细胞蛋白质组学试剂。我们的试剂是与该领域的杰出领导者（如迈克尔·J·福克斯基金会）合作建造的（请参见下面的“产品亮点”标签），这表明我们承诺与您的团队合作寻找新发现，为我们的客户带来新的选择和全面的解决方案研究神经系统疾病的解决方案。
