Macrophages are derived from the differentiation of monocytes in response to an infection or tissue damage. Their primary function is to recognize, engulf, and destroy pathogens, dying or dead cells and cellular debris. Macrophages are also professional antigen presenting cells that play a crucial role in modulating the host response, secreting an array of cytokines which aid in host defense, tissue repair, and immunoregulation.
The LEGENDplex™ Human Macrophage/Microglia Panel (13-plex) is a bead-based multiplex assay panel, which uses fluorescence-encoded beads suitable for use on various flow cytometers. It allows for simultaneous quantification 13 key targets involved in monocyte differentiation and macrophage function including IL-12p70, TNF-α, IL-6, IL-4, IL-10, IL-1β, Arginase, TARC, IL-1RA, IL-12p40, IL-23, IFN-γ, and IP-10. This assay panel provides higher detection sensitivity and broader dynamic range than traditional ELISA methods. The panel has been validated for use on cell culture supernatant, serum, and plasma samples.
The LEGENDplex™ Human Macrophage/Microglia Panel is designed to allow flexible customization within the panel. It can also be divided into sub-panels such as:
LEGENDplex™ Human M1 Macrophage Panel (8-plex)LEGENDplex™ Human M2 Macrophage Panel (6-plex)LEGENDplex™ Human M1/M2 Macrophage Panel (10-plex)
Please visit www.biolegend.com/legendplex for more information on how to mix and match within the panel.
Product Details Biolegend揭示出对神经系统以及影响神经系统的疾病的更好理解的研究可以转化为改善数百万生命的治疗方法。BioLegend提供广泛的产品组合，为您的神经科学实验提供解决方案，包括抗体，免疫测定溶液，重组蛋白，磁性细胞分离和单细胞蛋白质组学试剂。我们的试剂是与该领域的杰出领导者（如迈克尔·J·福克斯基金会）合作建造的（请参见下面的“产品亮点”标签），这表明我们承诺与您的团队合作寻找新发现，为我们的客户带来新的选择和全面的解决方案研究神经系统疾病的解决方案。
