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商品描述
DESCRIPTION:
Amacrocyclictrieneantibioticthatbindstoandinhibitsthemoleculartargetofrapamycin(mTOR)incomplexwithFKBP12.mToractsasanegativeregulatorofautophagyhenceinhibitonwithrapamycinleadstoactivationofautophagy.Rapamycinisapotentimmunosuppressantandhasanticancerandantifungalactivity.Inadditionitinhibitsinterleukin-2-inducedphosphorylationandactivationofp70S6kinase.
DATASHEET:
| Chemicalname | 23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine |
| CASnumber | 53123-88-9 |
| Molecularweight | 914.2 |
| Formula | C51H79NO13 |
| Solubility | Solubleinchloroform,DMSO,methanolorethanol |
| Purity | ≥98% |
| Storage | -20°C |
| Datasheet | A010-501 |
| Regulatorystatement | Productforresearchuseonly.Notintendedfordiagnosticortherapeuticuse. |


