DESCRIPTION:
Highlypotent,selectiveinhibitorofvacuolartypeH+-ATPase(V-ATPase).SelectiveforV-ATPaseoverotherATPhydrolyzingenzymessuchasF-ATPasesandtheH+/K+-ATPase(P-ATPase). Lysosomalprotonpumpinhibitor.Autophagyinhibitor-eitherbyblockingautophagosome-lysosomefusionorbyblockinglysosomaldegradation.
DATASHEET:
Chemicalname | (3Z,5E,7R,8S,9S,11E,13E,15S,16R)-8-Hydroxy-16-[(1S,2R,3S)-2-hydroxy-1-methyl-3-[(2R,4R,5S,6R)-tetrahydro-2,4-dihydroxy-5-methyl-6-(1-methylethyl)-2H-pyran-2-yl]butyl]-3,15-dimethoxy-5,7,9,11-tetramethyloxacyclohexadeca-3,5,11,13-tetraen-2-one |
CASnumber | 88899-55-2 |
Molecularweight | 622.8 |
Formula | C35H58O9 |
Solubility | DMSO,ethanolandmethanol,allupto5mg/ml |
Purity | >98% |
Storage | -20°C |
Datasheet | A010-502 |
Regulatorystatement | Productforresearchuseonly.Notintendedfordiagnosticortherapeuticuse. |