Description:
HumanPAK2kinase(UniProt:Q13177;NCBI:NM_002577)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesareregulatedbythesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK2isactivatedbyproteolyticcleavageduringcaspase-mediatedapoptosis,andmayplayaroleinregulatingtheapoptoticeventsinthedyingcell.PAK2KDisarecombinantwildtypehumanPAK2kinasedomain(aminoacids227–524offull-lengthhumanPAK2)expressedinE.coliandpurifiedtonearhomogeneitywithhighspecificactivity.
MolecularMassandPhosphorylation:
Thecalculatedmassis33,510.PAK2KDisfullyphosphorylatedatT402andpartiallyphosphorylatedatadditionalsiteswithmeasuredmassof33,593(1P),33,673(2P),33,753(3P),and33,834(4P).
StABIlityandStorage:
Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC.
Applications:
Enzymaticstudies,inhibitorscreen,andselectivityprofiling
Highconcentrationavailableforcrystallization
苏州蚂蚁淘生物技术研究所(ebiomall)销售Accelagen产品，美国Accelagen蛋白激酶/高纯蛋白/酶工具
Accelagen公司迅速的从基因研究到蛋白质研究成长起来的一个公司,它可以提供gene-to-protein全方位解决方案。Accelagen公司生产的重组蛋白已经广泛应用于基于结构的药物设计（SBDD）和高通量筛选（HTS）领域，用于各大药厂的药物研究与生产。其中Turbo3C （HRV3C）Protease、TurboTEV Protease、TurboNuclease是Accelagen公司极具性价比的优质产品。Accelagen重组蛋白表达和纯化服务可为生物学科研人员及药物研究提供高品质的重组蛋白。
H0101B
Turbo3C (HRV3C) Protease
Bulk
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Accelagen
H0101M
Turbo3C (HRV3C) Protease
10mg (10,000 Units)
￥25200
Accelagen
H0101S
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1mg (1,000 Units)
￥2800
Accelagen
N0103B
TurboNuclease
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Accelagen
N0103L
TurboNuclease
100,000 Units
￥4900
Accelagen
N0103M
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50,000 Units
￥2520
Accelagen
T0102B
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Bulk
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Accelagen
T0102L
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10mg (100,000 Units)
￥37800
Accelagen
T0102M
TurboTEV Protease
1mg (10,000 Units)
￥4200
Accelagen
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