Accelagen/PAK1KD (recombinant human PAK1 kinase domain)/K0104B/ Bulk

价格
面议
货号:K0104B
浏览量:127
品牌:Accelagen
服务
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商品描述
Description:
HumanPAK1kinase(UniProt:Q13153;NCBI:NM_002576)belongstoafamilyofp21-activatedkinases.Theseserine/threoninekinasesserveastargetsforthesmallGTPbindingproteinsCdc42andRacandhavebeenimplicatedinawiderangeofBIOLOGicalactivities.PAK1kinaseregulatescellmotilityandmorphology.PAK1KDisarecombinantwildtypehumanPAK1kinasedomain(aminoacids248–545offull-lengthhumanPAK1)expressedinE.coliandpurifiedtonearhomogeneity.PAK1KDdoesnothavetheinhibitoryswitchdomainandhashighspecificactivity.

MolecularMassandPhosphorylation:
Thecalculatedmassis33,646.PAK1KDisfullyphosphorylatedatT423andpartiallyphosphorylatedatadditionalsiteswithmeasuredmassof33,728(1P),33,808(2P),33,889(3P),and33,968(4P).

StABIlityandStorage:
Stableat-70oCfor12monthsfromdateofreceipt.Proteinshouldbethawedonice.Proteincanbeflash-frozeninliquidnitrogenandstoredat-70oC.

Applications:
Enzymaticstudies,inhibitorscreen,andselectivityprofiling
Highconcentrationavailableforcrystallization

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