absoluteantibody/Ab00217-10.0 Anti-CD4 [MT310]/Ab00217-10.0/ 200 µg

价格
¥5400.00
货号:Ab00217-10.0
浏览量:70
品牌:Absolute Antibody
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商品描述
Description:RecombinantmonoclonalantibodytoCD4.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaMT310.
SpeciesandIsotype:HumanIgG1,kappa
CloneNumber:MT310
UniProtAccessionNumberofTargetProtein:
PublishedApplication(s):WB;IP;IF;IHC-P;FC
PublishedSpeciesReactivity:Human;RhesusMonkey;CynomolgusMonkey
Immunogen:
Specificity:mt310bindstotheextracellulardomainD1ofCD4–thesamesiteastheHIV-1gp120-bindingsite
ApplicationNotes:mt310caninhibitgp120bindingtoCD4,whichblocksHIVinfectivityofCD4+Tlymphocytes,aswellasthebindingofMHCII,whichresultsintheblockofT-cellactivation,possIBLyleADIngtotheinductionofanergy.AntibodybindingtoCD4additionallycausestheinductionofGM-CSF,TNF-α(onlyafter20?h)andIL-10.
AntibodyFirstPublishedin:
Herzogetal.Monoclonalanti-CD4inarthritis.Lancet.1987Dec19;2(8573):1461-2.PMID:2892019Noteonpublication:Describestheuseofthisantibodyinimmunosuppression.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSonly.
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂,或者利用天然免疫系统来识别新的抗体候选物。对于这项服务,您可以提供免疫宿主生物的血清和B细胞,纯化的抗原用于免疫,或者只是告诉我们您的靶标,我们将做剩下的事情。鉴于其中之一,我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列,在交互式报告中提供具有蛋白质组学证据的扩展库,根据要求将抗体工程化为任何种类和同种型,以及我们提供的抗体表征数据获得。此服务是100%免版税的。