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蚂蚁淘在线 / 品牌中心 / Absolute Antibody / absoluteantibody/Ab00126-2.0 Anti-CD20 [10F381 (rituximab)]/Ab00126-2.0/ 200 µg
商品描述
Description:RecombinantmonoclonalantibodytoCD20.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthetherapeuticantibody10F381(rituximab).
CloneNumber:10F381(rituximab)
UniProtAccessionNumberofTargetProtein:P11836
PublishedApplication(s):FC
PublishedSpeciesReactivity:Human;RhesusMonkey;CynomolgusMonkey
Immunogen:HumanlymphoblastoidcelllineSB.
Specificity:CD20(HumanB-lymphocyte-restricteddifferentiationantigen,Bp35),isahydrophobictransmembraneproteinwithamolecularweightofapproximately35kDalocatedonpre-BandmatureBlymphocytes,andmostB-cellnon-Hodgkin"slymphomas,butisnotfoundonstemcells,pro-Bcells,normalplasmacellsorothernormaltissues.
AntibodyFirstPublishedin:
ReffME,CarnerK,ChambersKS,ChinnPC,LeonardJE,RaabR,NewmanRA,HannaN,AndersonDR.DepletionofBcellsinvivobyachimericmousehumanmonoclonalantibodytoCD20.Blood.1994Jan15;83(2):435-45.PMID:7506951Noteonpublication:Describesthemakingofthechimericmurineanti-CD20antibody2B8inconjunctionwithhumankappaandIgG1heavy-chainconstantregionsequences,andanalysedusingflowcytometry,invivopharmacologyandanimalsystemic/tissuetoxicitytests.
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂,或者利用天然免疫系统来识别新的抗体候选物。对于这项服务,您可以提供免疫宿主生物的血清和B细胞,纯化的抗原用于免疫,或者只是告诉我们您的靶标,我们将做剩下的事情。鉴于其中之一,我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列,在交互式报告中提供具有蛋白质组学证据的扩展库,根据要求将抗体工程化为任何种类和同种型,以及我们提供的抗体表征数据获得。此服务是100%免版税的。 ThischimericmouseantibodywasmadeusingthevariabledomainsequencesoftheoriginalHumanIgG1format,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:MouseIgG2a,kappaCloneNumber:10F381(rituximab)
UniProtAccessionNumberofTargetProtein:P11836
PublishedApplication(s):FC
PublishedSpeciesReactivity:Human;RhesusMonkey;CynomolgusMonkey
Immunogen:HumanlymphoblastoidcelllineSB.
Specificity:CD20(HumanB-lymphocyte-restricteddifferentiationantigen,Bp35),isahydrophobictransmembraneproteinwithamolecularweightofapproximately35kDalocatedonpre-BandmatureBlymphocytes,andmostB-cellnon-Hodgkin"slymphomas,butisnotfoundonstemcells,pro-Bcells,normalplasmacellsorothernormaltissues.
AntibodyFirstPublishedin:
ReffME,CarnerK,ChambersKS,ChinnPC,LeonardJE,RaabR,NewmanRA,HannaN,AndersonDR.DepletionofBcellsinvivobyachimericmousehumanmonoclonalantibodytoCD20.Blood.1994Jan15;83(2):435-45.PMID:7506951Noteonpublication:Describesthemakingofthechimericmurineanti-CD20antibody2B8inconjunctionwithhumankappaandIgG1heavy-chainconstantregionsequences,andanalysedusingflowcytometry,invivopharmacologyandanimalsystemic/tissuetoxicitytests.
ProductForm
Purification:ProteinAaffinitypurifiedSuppliedin:PBSwith0.02%Proclin300.
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°CConcentration:Seeviallabel.