absoluteantibody/Ab00295-7.1 Anti-Ly6G [1A8]/Ab00295-7.1/ 200 µg

价格
¥6384.00
货号:Ab00295-7.1
浏览量:127
品牌:Absolute Antibody
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Description:RecombinantmonoclonalantibodytoLy6G.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridoma1A8.
SpeciesandIsotype:RatIgG2a,kappa
CloneNumber:1A8
UniProtAccessionNumberofTargetProtein:P35461
AlternativeName(s)ofTarget:Ly-6G;GR-1;GR1;Lymphocyteantigen6G
PublishedApplication(s):FC;depletion
PublishedSpeciesReactivity:Mouse
Immunogen:LEW/Nratsimmunizedwith1.5x10E8Ly-6G-transfectedEL4Jcells
Specificity:RecognisesthemurineGPI-anchoredproteinLy6G,aMarkerofgranulocytedifferentiation,maturationand,togetherwithLy6C,acomponentoftheGranulocyteReceptor-1Antigen(Gr-1).Unlikeanothercommonlyusedclone,RB6-8C5,1A8doesnotbindLy6C.
ApplicationNotes:Neutrophilsarecrucialcomponentsofourimmunesystem.Ly6Gishighlyexpressedonneutrophils,whichallowsthe1A8clonetobeusednotonlyindetectionofneutrophils,butalsoinselectivedepletioninvivo.Itmayalsobeusedasanegativeselectionmarkerforbone-marrowderivedmacrophages,whichshouldbeLy6G(-)andF4/80(+)(seeourF4/80rangeofantibodies).
AntibodyFirstPublishedin:
FlemingTJ,FlemingML,MalekTR.SelectiveexpressionofLy-6Gonmyeloidlineagecellsinmousebonemarrow.RB6-8C5mAbtogranulocyte-differentiationantigen(Gr-1)detectsmembersoftheLy-6family.JournalofImmunologyPMID:8360469Noteonpublication:Describesproductionof1A8andidentificationofLy6Gasitstarget.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSonly.
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂,或者利用天然免疫系统来识别新的抗体候选物。对于这项服务,您可以提供免疫宿主生物的血清和B细胞,纯化的抗原用于免疫,或者只是告诉我们您的靶标,我们将做剩下的事情。鉴于其中之一,我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列,在交互式报告中提供具有蛋白质组学证据的扩展库,根据要求将抗体工程化为任何种类和同种型,以及我们提供的抗体表征数据获得。此服务是100%免版税的。