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蚂蚁淘在线 / 品牌中心 / Absolute Antibody / absoluteantibody/Ab00812-10.3 Anti-E-protein DIII (LR) [ZV-67]/Ab00812-10.3/ 200 µg
商品描述
Description:RecombinantmonoclonalantibodytoE-proteinDIII(LR).ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaZV-67.ThisantibodywascreatedusingourproprietaryFcSilent™engineeredFcdomaincontainingkeypointmutationsthatabrogatebindingtoFcgammareceptors.
CloneNumber:ZV-67
UniProtAccessionNumberofTargetProtein:
PublishedApplication(s):NTRL;crystallization;SPR;FC
PublishedSpeciesReactivity:ZikaVirus
Immunogen:Thisantibodywasgeneratedbyinfectingmicewith1000FFUofZIKVMR-766followedbyaboosterat30dpost-infectionofZIKVH/PF/2013,respectivelyandgivenafinalintravenousboostwithliveZIKVDIII(aminoacids299to407oftheZIKVEprotein))
Specificity:ZV-67bindstotheZikavirusenvelopeproteinatdomainIII(DIII,LR).Nocross-reactivitywithothertestedflaviviruseshasbeenreported.
ApplicationNotes:TheoriginalmouseIgG2cformathasbeenshowntohaveneutralizingactivityandhasbeenusedtolabelZIKVinfectedcells(4%PFAfixation,0.1%saponinpermeABIlization).
AntibodyFirstPublishedin:
Zhaoetal.StructuralBasisofZikaVirus-SpecificAntibodyProtection.Cell.2016Aug11;166(4):1016-27Noteonpublication:Describesthegenerationandcharacterisationofthisantibody.
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂，或者利用天然免疫系统来识别新的抗体候选物。对于这项服务，您可以提供免疫宿主生物的血清和B细胞，纯化的抗原用于免疫，或者只是告诉我们您的靶标，我们将做剩下的事情。鉴于其中之一，我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列，在交互式报告中提供具有蛋白质组学证据的扩展库，根据要求将抗体工程化为任何种类和同种型，以及我们提供的抗体表征数据获得。此服务是100％免版税的。 ThischimerichumanantibodywasmadeusingthevariabledomainsequencesoftheoriginalMouseIgG2cformat,forimprovedcompatibilitywithexistingreagents,assaysandtechniques.
SpeciesandIsotype:HumanIgG1,FcSilent™,kappaCloneNumber:ZV-67
UniProtAccessionNumberofTargetProtein:
PublishedApplication(s):NTRL;crystallization;SPR;FC
PublishedSpeciesReactivity:ZikaVirus
Immunogen:Thisantibodywasgeneratedbyinfectingmicewith1000FFUofZIKVMR-766followedbyaboosterat30dpost-infectionofZIKVH/PF/2013,respectivelyandgivenafinalintravenousboostwithliveZIKVDIII(aminoacids299to407oftheZIKVEprotein))
Specificity:ZV-67bindstotheZikavirusenvelopeproteinatdomainIII(DIII,LR).Nocross-reactivitywithothertestedflaviviruseshasbeenreported.
ApplicationNotes:TheoriginalmouseIgG2cformathasbeenshowntohaveneutralizingactivityandhasbeenusedtolabelZIKVinfectedcells(4%PFAfixation,0.1%saponinpermeABIlization).
AntibodyFirstPublishedin:
Zhaoetal.StructuralBasisofZikaVirus-SpecificAntibodyProtection.Cell.2016Aug11;166(4):1016-27Noteonpublication:Describesthegenerationandcharacterisationofthisantibody.
ProductForm
Purification:ProteinAaffinitypurifiedSuppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.
