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蚂蚁淘在线 / 品牌中心 / Absolute Antibody / absoluteantibody/Ab00811-2.0 Anti-E-protein DIII (C-C’) [ZV-64]/Ab00811-2.0/200 µg
商品描述
Description: Recombinant monoclonal antibody to E-protein DIII (C-C'). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma ZV-64.
Clone Number: ZV-64
UniProt Accession Number of Target Protein:
Published Application(s): NTRL; crystallization; SPR; FC
Published Species Reactivity: Zika Virus
Immunogen: This antibody was generated by infecting mice with 1000 FFU of ZIKV MR-766 followed by a booster at 30d post-infection of ZIKV H/PF/2013, respectively and given a final intravenous boost with live ZIKV DIII (amino acids 299 to 407 of the ZIKV E protein))
Specificity: ZV-64 binds to the Zika virus envelope protein at domain III (DIII, C-C’ loop). No cross-reactivity with other tested flaviviruses has been reported.
Application Notes: The original mouse IgG2c format has been shown to have neutralizing activity and has been used to label ZIKV infected cells (4% PFA fixation, 0.1% saponin permeabilization).
Antibody First Published in:
Zhao et al. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. 2016 Aug 11;166(4):1016-27 Note on publication: Describes the generation and characterisation of this antibody.
Supplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
Important note – This product is for research use only. It is not intended for use in therapeutic or diagnostic
procedures for humans or animals. Absolute Antibody我们现在与Digital Proteomics合作提供多克隆永生化服务。这意味着您可以生产可复制且不受限制的多克隆试剂，或者利用天然免疫系统来识别新的抗体候选物。对于这项服务，您可以提供免疫宿主生物的血清和B细胞，纯化的抗原用于免疫，或者只是告诉我们您的靶标，我们将做剩下的事情。鉴于其中之一，我们可以提供多达10条由发现引擎选择的重链序列和10条轻链序列，在交互式报告中提供具有蛋白质组学证据的扩展库，根据要求将抗体工程化为任何种类和同种型，以及我们提供的抗体表征数据获得。此服务是100％免版税的。 This reformatted mouse antibody was made using the variable domain sequences of the original Mouse IgG2c format, for improved compatibility with existing reagents, assays and techniques.
Species and Isotype: Mouse IgG2a, kappaClone Number: ZV-64
UniProt Accession Number of Target Protein:
Published Application(s): NTRL; crystallization; SPR; FC
Published Species Reactivity: Zika Virus
Immunogen: This antibody was generated by infecting mice with 1000 FFU of ZIKV MR-766 followed by a booster at 30d post-infection of ZIKV H/PF/2013, respectively and given a final intravenous boost with live ZIKV DIII (amino acids 299 to 407 of the ZIKV E protein))
Specificity: ZV-64 binds to the Zika virus envelope protein at domain III (DIII, C-C’ loop). No cross-reactivity with other tested flaviviruses has been reported.
Application Notes: The original mouse IgG2c format has been shown to have neutralizing activity and has been used to label ZIKV infected cells (4% PFA fixation, 0.1% saponin permeabilization).
Antibody First Published in:
Zhao et al. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. 2016 Aug 11;166(4):1016-27 Note on publication: Describes the generation and characterisation of this antibody.
Product Form
Purification: Protein A affinity purifiedSupplied in: PBS with preservative (0.02% Proclin 300)
Storage Recommendation: Store at 4°C for up to 3 months. For longer term storage aliquot into small volumes and store at -20°C
Concentration: See vial label.
