品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com

Bpsbioscience/TLR9/ NF-κB Reporter – HEK293 Recombinant Cell Line/60485/2 vials

价格
¥28500.00
货号:60485
浏览量:127
品牌:BPS Bioscience
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Background:
The family of Toll-like receptors (TLRs) acts as primary sensors that detect a wide variety of microbial components and elicit innate immune responses.

Human TLR9 recognizes specific unmethylated CpG DNA motifs prevalent in microbial but not vertebrate genomic DNA, leading to innate and acquired immune responses. Stimulation of TLR9 triggers a signaling cascade leading to the activation of the transcription factor NF-κB, which controls the expression of an array of inflammatory cytokine genes.

Description:
Recombinant HEK293 cell expressing firefly luciferase gene under the control of NF-κB response elements with constitutive expression of human TLR9 (Toll-like receptor 9, also been designated as CD289, a member of the toll-like receptor (TLR) family. GenBank Accession No. NM_017442)
Synonym(s):
TLR TLR-9
Mycoplasma Testing:
The cell line has been screened using the PCR-based Venor®GeM Mycoplasma Detection kit (Sigma-Aldrich #MP0025) to confirm the absence of Mycoplasma species.
Format:
Each vial contains ~2 x 10^6 cells in 1 ml of 10% DMSO
Storage / Stability:
Immediately upon receipt, store in liquid nitrogen.
Application(s):
Screen for activators or inhibitors of TLR9 signaling in a cellular context and • characterize the biological activity of TLR9 and its interactions with ligands
Notes:

Contact us for pricing.

License Disclosure:Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit use of this cell line in humans or for therapeutic or drug use. The license does not permit modification of the cell line in any way. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. BPS does not warrant the suitability of the cell line for any particular use, and does not accept any liability in connection with the handling or use of the cell line. Modifications of this cell line, transfer to another facility, or commercial use of the cells may require a separate license and additional fees; contact sales@bpsbioscience.com for details. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.

Scientific Category:
Immunotherapy
Product Type:
Cell Line
Data shown is lot-specific. Contact us for specific information on other lots.
BPS Bioscience生物素化,生物素标记通常用于蛋白质和其他目标分子的非放射性标记和纯化。生物素标记利用生物素(维生素H)与抗生物素蛋白或抗生蛋白链菌素之间异常强的相互作用。生物素与抗生物素蛋白或抗生蛋白链菌素的亲和力是已知的蛋白质和配体最强的非共价相互作用之一,在10 -15附近表现出解离常数(K d)。此外,这种相互作用可抵抗高或低pH,高盐浓度,极端温度和变性剂。生物素-亲和素相互作用的这些性质使其可用于纯化和/或检测目的蛋白质。BPS具有许多蛋白质,这些蛋白质已通过化学方法通过各种反应基团以及使用AviTag TM  技术进行酶促生物素标记。BPS的生物素化产品组合包括用于标记伯胺和仲胺,炔基,硫醇,羧基和磷酸基以及各种PEG基团的试剂。这种灵活性使研究人员能够满足他们所有的生物素化需求。