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蚂蚁淘在线 / 品牌中心 / BPS Bioscience / Bpsbioscience/S-adenosyl homocysteine, Fluorescein-labeled/52012/20 µl
商品描述
MW:773.8Da
Tag(s):Fluorescein
CASRegistry#:979-92-0(SAH)
Background:
S-Adenosyl-L-homocysteineisanaminoacidderivativeusedinseveralmetabolicpathwaysinmostorganisms.S-Adenosyl-L-homocysteine(SAH)isanaminoacidderivativeandanintermediate,by-product,ormodulatorofseveralmetabolicpathways,includingtheactivatedmethylcycleandcysteinebiosynthesis.SAHisformedbythedemethylationofS-adenosyl-L-methionine.ItisalsoaproductofS-adenosyl-methionine(SAM)-dependentmethylationofBIOLOGicalmolecules,includingDNA,RNA,andhistonesandotherproteins.Inhibitorsthatblockitshydrolysisarebeingdevelopedasanti-viral,anti-parasitic,anti-arthriticandimmunosuppressiveagents.
Description:
S-adenosylhomocysteineconjugatedtofluorescein.
Synonym(s):
FITC-SAH,AdoHCys-FITC,S-adenosylhomocysteine,FITC,SAH-FITC
SuppliedAs:
DMSOsolution(12.5µM)
Format:
DMSOsolution
Storage/StABIlity:
Atleast6monthsfromdateofreceipt,whenstoredasdirected
Application(s):
Studyenzymekinetics,andscreensmallmolecularinhibitorsofS-adenosylhomocysteinehydrolaseandhistonemethyltransferasesfordrugdiscoveryandHTSapplications.
Reference(s):
1.CowardJK,SliszEP.JMedChem.1973May;16(5):460-3.
2.FinkelsteinJD.ClinChemLabMed.2007;45(12):1694-9.
2.FinkelsteinJD.ClinChemLabMed.2007;45(12):1694-9.
Warning(s):
Protectfromlight.Avoidfreeze/thawcycles.
ScientificCategory:
Methyltransferase
ProductType:
Reagent
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