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公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Description:
TheSMARCA4TR-FRETAssayKitisdesignedtomeasuretheinhibitionofSMARCA4bindingtoitssubstrateinahomogeneous384reactionformat.ThisFRET-basedassayrequiresnotime-consumingwashingsteps,makingitespeciallysuitableforhighthroughputscreeningapplications.Theassayprocedureisstraightforwardandsimple;asamplecontainingterbium-labeleddonor,dye-labeledacceptor,SMARCA4,substrate,andaninhibitorisincubatedfor120minutes.Then,thefluorescenceintensityismeasuredusingafluorescencereader.
UniProt
P51532
Synonym(s):
SMARCA4,BRG1,ActinLike6A,ACTL6A,SWI/SNFRelated,MatrixAssociated,ActinDependentRegulatorOfChromatin,SubfamilyA,Member4,SWI/SNFRelated,MatrixAssociated,ActinDependentRegulatorOfChromatin,SubfamilyB,Member1,SMARCB1
Format:
COMPONENTS:
Instructionsforuse:
Seeassaykitdatasheetfordetailedprotocol
Storage/StABIlity:
Stableatleast6monthsfromdateofreceipt,whenstoredasdirected.Kitcomponentsrequiredifferentstorageconditions.Besuretostoreeachcomponentatthepropertemperatureuponarrival.
Application(s):
GreatforscreeningsmallmolecularinhibitorsfordrugdiscoveryandHTSapplications.
Reference(s):
Schiaffino-Ortega,S.,etal.,2014.J.Hematol.Oncol.7:81.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Bromodomain
ProductType:
Assaykit
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