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商品描述
Species:Human
HostSpecies:E.coli
MW:12kDa
Genbank#:NM_032574
Tag(s):N-terminalHis-tag
a.a:2–99(end)
Background:
AspartoftheMLL1/MLLcomplex,involvedinthemethylationofhistoneH3atLys-4,particularlytrimethylation.HistoneH3Lys-4methylationrepresentsaspecifictagforepigenetictranscriptionalactivation.MayplaysomeroleinhistoneH3acetylation.Inateratocarcinomacell,playsacrucialroleinretinoicacid-induceddifferentiationalongtheneurallineage,regulatinggeneinductionandH3Lys-4methylationatkeydevelopmentalloci.Mayalsoplayanindirectordirectroleinendosomaltransport.
Description:
Humandpy-30homolog,orDPY30,GenBankAccessionNo.NM_032574,a.a.2-99(end)withN-terminalHis-tag,MW=12kDa,expressedinanE.coliexpressionsystem.
UniProt
Q9C005
Synonym(s):
DPY30,HDPY30
Format:
Aqueousbuffersolution
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Xu,Z.,etal.,JCellBiol.2009Aug10;186(3):343-53
2.Patel,A.,etal.,JBiolChem.2009Sep4;284(36):24242-56
2.Patel,A.,etal.,JBiolChem.2009Sep4;284(36):24242-56
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Miscellaneous
ProductType:
RecombinantProtein
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