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商品描述
Species:Human
HostSpecies:E.coli
MW:63.6kDa
Genbank#:NM_032438
Tag(s):N-terminalGST-tag
a.a:229–547
Background:
PcGproteinsmaintainthetranscriptionallyrepressivestateofgenes,probablyviaamodificationofchromatin,renderingitheritablychangedinitsexpressibility.Itsassociationwithachromatin-remodelingcomplexsuggeststhatitmaycontributetopreventexpressionofgenesthattriggerthecellintomitosis.
Description:
Humanlethal(3)malignantbraintumor-likeprotein3(L3MBTL3),GenBankAccessionNo.NM_032438,a.a.229-547withN-terminalGST-tag,MW=63.6kDa,expressedinanE.colicellexpressionsystem.
UniProt
Q96JM7
Synonym(s):
lethal(3)malignantbraintumor-likeprotein3
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,1.8mMglutathione,0.007%Tween-20,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
≥ 6monthsat-80°C
Application(s):
UsefulforthestudyofPolycombgroup(PcG)proteins,proteinbindingassays,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.James,L.I., etal.,NatChemBiol.
2013Mar;9(3):184-91.
2.Arai,S.,Miyazaki,T., EMBOJ. 2005
May18;24(10):1863-73.
Warning(s):
Avoidfreeze/thawcycles
ScientificCategory:
Methyl-lysineReader
ProductType:
RecombinantProtein
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