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商品描述
Species:Human
HostSpecies:Sf9insectcells
MW:125kDa
Genbank#:NM_001429
Tag(s):N-terminalHis-GST-tags
a.a:965–1810
Description:
HumanE1Abindingproteinp300,alsoknownasEP300,KAT3B,orRSTS2,GenBankAccessionNo.NM_001429,a.a.965-1810,withN-terminalHis-GST-tag,MW=125kDa,expressedinSf9cellsviaabaculovirusexpressionsystem.
UniProt
Q09472
Synonym(s):
EP300,KAT3B,RSTS2,E1Abindingprotein
SpecificActivity:
≥357pmole/min/µg
AssayConditions:
AssayedwiththeBPSBioscienceFluorogenicp300AssayKit,Cat.#50092,permanufacturer"sinstructions.
Formulation:
40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,200mMimidazole,and20%glycerol.
Format:
Aqueousbuffersolution
Storage/StABIlity:
>6monthsat–80°C
Application(s):
Usefulforthestudyofenzymekinetics,screeninginhibitors,andselectivityprofiling.
Reference(s):
1.Gui,Y.,etal.,Nat.Genet.2011Aug7;43(9):875–878.
2.Morin,R.D.,etal.,Nature.2011Jul27;476(7360):298–303.
3.Zhao,Z.,etal.,BrainRes.Bull.2011Oct10;86(3-4):189–194.
ProductSpecificReference(s):
1.Furdas,S.D.etal.,Med.Chem.Commun.2014;5:1856-1862.
2.Liao,D.,etal.,Cancer.Epigenetics.2005;1238:539-548.
Warning(s):
Avoidfreeze/thawcycles.
ScientificCategory:
Acetyltransferase
ProductType:
RecombinantProtein
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