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商品描述
MW:258.2Da
CASRegistry#:2627-69-2
Formula:C9H14N4O5
Description:
AICAR,alsoknownasacadesine,isanadenosineregulatingagentandAMPKactivator.AICARwasfoundtoactivateAMP-activatedproteinkinase(AMPK)inskeletalmuscle,inhibitacetyl-CoAcarboxylase,reducemalonyl-CoA,andincreasefattyacidoxidationandglucoseuptake.Note:Thisproductisnot5"-phosphorylated.
Synonym(s):
Acadesine,AIC-Riboside,5-Aminoimidazole-4-carboxamideriboside
Purity:
≥99%
Solubility:
SolubleinDMSOat40mg/ml;solubleinethanolat2mg/mlwithwarming;solubleinwaterat20mg/mlwithwarming
Format:
Tanpowder
Storage/StABIlity:
Storeatorbelow–20°C.Solidformisstableatleast12monthsfromdateofreceipt,whenstoredasdirected.Donotstoreaqueoussolutionsformorethanoneday.
Reference(s):
Merrill,G.F.,etal.Am.J.Physiol.273:E1107-E1112(1997).
ScientificCategory:
ACC
ProductType:
Inhibitor
Datashownislot-specific.Contactusforspecificinformationonotherlots.