avanti polar lipids蚂蚁淘在线

Info

18:0 DDAB

Dimethyldioctadecylammonium (Bromide Salt)

Incorporation of the glycolipid trehalose 6,6"-dibehenate (TDB) into cationic liposomes composed of the quaternary ammonium compound dimethyldioctadecylammonium (DDA) produce an adjuvant system which induces a powerful cell-mediated immune response and a strong antibody response, desirable for a high number of disease targets.

Data

Hygroscopic

No

Light Sensitive

No

Molecular Formula

C₃₈H₈₀NBr

Percent Composition

C 72.34%, H 12.78%, Br 12.66%, N 2.22%

Purity

>99%

Stability

1 Years

Storage Temperature

-20°C

CAS Number

3700-67-2 CAS Registry Number is a Registered Trademark of the American Chemical Society

FormulaWeight

630.952

Exact Mass

629.547

Synonyms

dimethyldioctadecylammonium (bromide salt)DDA

Downloads

ChemDraw File
3D Structure
Structure
Safety Data Sheet
Safety Data Sheet

References

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PubMed ID: 32619745

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PubMed ID: 32315188

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PubMed ID: 32251383

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PubMed ID: 28190740

Derrick SC, Yabe I, Morris S, Cowley S. Induction of Unconventional T Cells by a Mutant Mycobacterium bovis BCG Strain Formulated in Cationic Liposomes Correlates with Protection against Mycobacterium tuberculosis Infections of Immunocompromised Mice. Clin Vaccine Immunol. 2016 Jul 5;23(7):638-47. doi: 10.1128/CVI.00232-16. PMID: 27226281; PMCID: PMC4933783.

PubMed ID: 27226281

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PubMed ID: 25957906

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PubMed ID: 25905680

Gallez A, Palazzo C, Blacher S, Tskitishvili E, Noël A, Foidart JM, Evrard B, Pequeux C, Piel G. Liposomes and drug-in-cyclodextrin-in-liposomes formulations encapsulating 17β-estradiol: An innovative drug delivery system that prevents the activation of the membrane-initiated steroid signaling (MISS) of estrogen receptor α. Int J Pharm. 2020 Jan 5;573:118861. doi: 10.1016/j.ijpharm.2019.118861. Epub 2019 Nov 22.

PubMed ID: 31765774

Faria MJ, Machado R, Ribeiro A, Gonçalves H, Real Oliveira MECD, Viseu T, das Neves J, Lúcio M. Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention. Pharmaceutics. 2019 Sep 18;11(9). pii: E485. doi: 10.3390/pharmaceutics11090485.

PubMed ID: 31540519

Silva AM, Martins-Gomes C, Fangueiro JF, Andreani T, Souto EB. Comparison of antiproliferative effect of epigallocatechin gallate when loaded into cationic solid lipid nanoparticles against different cell lines. Pharm Dev Technol. 2019 Sep 11:1-7. doi: 10.1080/10837450.2019.1658774. [Epub ahead of print]

PubMed ID: 31437118

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PubMed ID: 31326598

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Bicelle Preparation

Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation. Reference/Protocol

avanti polar lipids/18:0 DDAB/25mg/890810P-25mg

890810 | 18:0 DDAB

Dimethyldioctadecylammonium (Bromide Salt)

18:0 DDAB

Dimethyldioctadecylammonium (Bromide Salt)