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商品描述
ProductDescription
| CatalogueNumber: | AN00023 |
| ProductName: | anti-AATFantibody |
| Form: | liquid |
| Host: | Rabbit |
| Clonity: | polyclonal |
| Isotope: | IgG |
| Storage: | PBSwith0.02%sodiumazideand50%glycerolpH7.3,-20â&BDquo;ƒfor24months(Avoidrepeatedfreeze/thawcycles.) |
| Background: | MayfunctionasageneralinhibitorofthehistonedeacetylaseHDAC1.BindingtothepocketregionofRB1maydisplaceHDAC1fromRB1/E2Fcomplexes,leADIngtoactivationofE2Ftargetgenesandcellcycleprogression.Conversely,displacementofHDAC1fromSP1boundtotheCDKN1ApromoterleadstoincreasedexpressionofthisCDKinhibitorandblockscellcycleprogression.AlsoantagonizesPAWRmediatedinductionofaberrantamyloidpeptideproductioninAlzheimerdisease(presenileandseniledementia),althoughthemolecularbasisforthisphenomenonhasnotbeendescribedtodate. |
| Immunogen: | apoptosisantagonizingtranscriptionfactor |
| Synonyms: | AATF,CHE1,CHE1,DED,ProteinAATF,RbbindingproteinChe1,Traube |
| CalculatedMW: | 63kDa |
| Specificity: | Human,Mouse,Rat |
| TestedApplication: | ELISA,WB,IF |
| RecommendedDilution: | WB:1:200-1:2000;IF:1:10-1:100 |
| WBDilution: | mousebraintissueweresubjectedtoSDSPAGEfollowedbywesternblotwithAATFantibodyatdilutionof1:800 |
| GeneID: | 26574 |
| Location: | Nucleus |
TRC抗病毒药抗病毒药物是专门用于治疗病毒感染的一类药物。大多数抗病毒药可用于特定的病毒感染，而某些抗病毒药可有效对抗多种病毒。抗病毒药物并非旨在消灭其靶病原体，而是抑制病毒复制的特定阶段。这可能包括阶段，例如与宿主细胞的附着，病毒成分的复制或传染性病毒颗粒的释放。发现我们完整系列的抑制剂和调节剂，以及结构单元，代谢产物，杂质和标记的同位素。 
