Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1. Modulates transcription activation by retinoic acid (RA) receptors, including RARA. Plays a role in regulating retinoic acid-dependent proliferation of hepatocytes.||Source:|Recombinant protein corresponding to aa891-1012 from human TRIM24, fused to His-SUMO-Tag at N-terminal, expressed in E. coli. ||Molecular Weight: |~30.5kD||AA Sequence:|KKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPLTVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFNEPDSEVANAGIKLENYFEELLKNLYPEKRFPK||Storage and Stability: |May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Source: Recombinant, E. coli|Purity: ≥90% (SDS-PAGE)|Concentration: As reported|Form: Supplied as a liquid in Tris, 50% glycerol.||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. 2018年8月，蚂蚁淘成为UnitedStatesBiological（简称USBio）代理商，UnitedStatesBiological也简称为USBiological。 欢迎广大客户咨询订货，在线QQ：3507623898 4000-520-616 最主要的一抗产品： 144747-FITC Anti-IL-6(BCellstimulatoryfactor2)(FITC) Pab rabbit human IgG Hu FITC $592 IL6 WB 100ul 144764-FITC Anti-Interferongamma(IFN-gamma)(FITC) Pab rabbit rat IgG Rt FITC $592 IFNG E,IHC,IP,N,WB 100ul 144739-FITC Anti-IL-3(Hematopoieticgrowthfactor,Mastcellgrowthfactor)(FITC) Pab rabbit human IgG Hu FITC $592 IL3 E,IHC,IP,N,WB 100ul 144964-FITC Anti-NFKB1(KBF1,NF-kappaB,NFkappaB,NF-kB1,NFKB-p50,EBP-1,p50,p105,TRANSCRIPTIONFACTORNFKB1,DNA-bindingfactorKBF1,NFKBp50,INCLUDED,NFKBp105,INCLUDED,NuclearfactorofkappalightpolypeptidegeneenhancerinBCells1)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 NFKB1 WB 100ul 303092-FITC Anti-ACE(ACE1,ACET,ACE_HUMAN,ACE1,AngiotensinConvertingEnzymeSomaticIsoform,AngiotensinConvertingEnzymeTestisSpecificIsoform,AngiotensinIConvertingEnzyme,AngiotensinIConvertingEnzyme1,AngiotensinIConvertingEnzymePeptidylDipeptidaseA1,Angiotensin-convertingEnzyme,Carboxycathepsin,CD143,CD143,CD143Antigen,DCP1,DCP,DCP1,DipeptidylCarboxypeptidase1,DipeptidylCarboxypeptidaseI,KininaseII,MVCD3,PeptidaseP,PeptidylDipeptidaseA,SolubleForm,TesticularECA)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $592 IHC,WB 100ul 145142-FITC Anti-SCF(Mastcellgrowthfactor)(FITC) Pab rabbit human IgG Hu FITC $592 KITLG E,WB 100ul 145147-FITC Anti-SDHA(FlavoproteinsubunitofcomplexII)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 SDHA IHC,WB 100ul 145286-FITC Anti-TNC(Hxb,Hexabrachion,Tenascin-C,TN-C,TN,CYTOTACTIN,hexabrachion(tenascinC,cytotactin),hexabrachion(tenascin),MGC167029)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 TNC IHC,WB 100ul 303394-FITC Anti-Interleukin1Beta(IL1beta,Catabolin,H1,Hematopoietin1,IFNbetaInducingFactor,IL1,IL1beta,IL1B,IL-1beta,IL1Beta,IL1B,IL1B_HUMAN,IL1F2,Interleukin1betaPrecursor,Interleukin-1beta,LAF,OAF,OsteoclastActivatingFactor,Preinterleukin1beta,Preinterleukinbeta,ProInterleukin1beta)(FITC) Pab rabbit rat IgG Rt FITC $592 E,WB 100ul 303592-FITC Anti-SerumAmyloidP(9.5Salpha1Glycoprotein,9.5Salpha-1-glycoprotein,AmyloidPComponentSerum,APCS,PentaxinRelated,Pentraxin2,PTX2,PTX2,SAMP_HUMAN,SAP,SerumAmyloidPComponent,SerumAmyloidP-component(1-203))(FITC) Pab rabbit rat IgG Rt FITC $592 IHC,WB 100ul 144120-HRP Anti-Actin(Gamma-actin)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 ACTG1 IHC,WB 100ul 144129-HRP Anti-ADAMTS2(ProcollagenIN-proteinase)(HRP) Pab rabbit human IgG Hu,Rt HRP $628 ADAMTS2 IHC,WB 100ul 144160-HRP Anti-ANGPTL3(ANG-5,ANGPT5,Angiopoietin-5)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 ANGPTL3 WB 100ul 144183-HRP Anti-ApoptosisregulatorBcl-2(HRP) Pab rabbit human IgG Hu HRP $592 BCL2 E,IP,N,WB 100ul 144190-HRP Anti-AQP3(Aquaglyceroporin-3)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 AQP3 IC,IHC,WB 100ul