品牌分类
品牌咨询
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Ponatinib is a novel potent, orally available small molecule multitargeted kinase inhibitor. Ponatinib inhibits both native and mutant BCR-ABL. Ponatinib is used in the treatment of chronic myeloid leukemia (CML) with BCR-ABL kinase inhibitors. Ponatinib is the active ingredient in the drug product sold under the trade name Iclusig®, currently approved in at least one country for use in patients with chronic myeloid leukemia (CML) and Philadelphia chromosome positive (Ph+) acute lymphoblastic leukemia.||Synonyms:|3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig||CAS No:|943319-70-8|HCl salt: 114544-31-8||Molecular Formula:|C29H27F3N6O||Molecular Weight:|532.56||Appearance|White to off-white powder||Purity:|≥99% (HPLC)||Melting Point:|>160°C (dec.)||Solubility:|Soluble in DMSO at 50 mg/mL; soluble in ethanol at 25 mg/mL with warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-10 µM; buffers, serum, or other additives may increase or decrease the aqueous solubility||Method for Determining Identity: |Proton NMR (DMSO-d6) Spectroscopic and Mass Spectrometric Analysis||Storage and Stability: |May be stored at RT for short-term only. Long-term storage is recommended at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Light sensitive. Store under inert atmosphere.Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards: All products should be handled by qualified personnel only, trained in laboratory procedures.
2018年8月,蚂蚁淘成为UnitedStatesBiological(简称USBio)代理商,UnitedStatesBiological也简称为USBiological。
欢迎广大客户咨询订货,在线QQ:3507623898
4000-520-616
最主要的一抗产品:
144747-FITC
Anti-IL-6(BCellstimulatoryfactor2)(FITC)
Pab
rabbit
human
IgG
Hu
FITC
$592
IL6
WB
100ul
144764-FITC
Anti-Interferongamma(IFN-gamma)(FITC)
Pab
rabbit
rat
IgG
Rt
FITC
$592
IFNG
E,IHC,IP,N,WB
100ul
144739-FITC
Anti-IL-3(Hematopoieticgrowthfactor,Mastcellgrowthfactor)(FITC)
Pab
rabbit
human
IgG
Hu
FITC
$592
IL3
E,IHC,IP,N,WB
100ul
144964-FITC
Anti-NFKB1(KBF1,NF-kappaB,NFkappaB,NF-kB1,NFKB-p50,EBP-1,p50,p105,TRANSCRIPTIONFACTORNFKB1,DNA-bindingfactorKBF1,NFKBp50,INCLUDED,NFKBp105,INCLUDED,NuclearfactorofkappalightpolypeptidegeneenhancerinBCells1)(FITC)
Pab
rabbit
human
IgG
Hu,Mo,Rt
FITC
$628
NFKB1
WB
100ul
303092-FITC
Anti-ACE(ACE1,ACET,ACE_HUMAN,ACE1,AngiotensinConvertingEnzymeSomaticIsoform,AngiotensinConvertingEnzymeTestisSpecificIsoform,AngiotensinIConvertingEnzyme,AngiotensinIConvertingEnzyme1,AngiotensinIConvertingEnzymePeptidylDipeptidaseA1,Angiotensin-convertingEnzyme,Carboxycathepsin,CD143,CD143,CD143Antigen,DCP1,DCP,DCP1,DipeptidylCarboxypeptidase1,DipeptidylCarboxypeptidaseI,KininaseII,MVCD3,PeptidaseP,PeptidylDipeptidaseA,SolubleForm,TesticularECA)(FITC)
Pab
rabbit
human
IgG
Hu,Mo,Rt
FITC
$592
IHC,WB
100ul
145142-FITC
Anti-SCF(Mastcellgrowthfactor)(FITC)
Pab
rabbit
human
IgG
Hu
FITC
$592
KITLG
E,WB
100ul
145147-FITC
Anti-SDHA(FlavoproteinsubunitofcomplexII)(FITC)
Pab
rabbit
human
IgG
Hu,Mo,Rt
FITC
$628
SDHA
IHC,WB
100ul
145286-FITC
Anti-TNC(Hxb,Hexabrachion,Tenascin-C,TN-C,TN,CYTOTACTIN,hexabrachion(tenascinC,cytotactin),hexabrachion(tenascin),MGC167029)(FITC)
Pab
rabbit
human
IgG
Hu,Mo,Rt
FITC
$628
TNC
IHC,WB
100ul
303394-FITC
Anti-Interleukin1Beta(IL1beta,Catabolin,H1,Hematopoietin1,IFNbetaInducingFactor,IL1,IL1beta,IL1B,IL-1beta,IL1Beta,IL1B,IL1B_HUMAN,IL1F2,Interleukin1betaPrecursor,Interleukin-1beta,LAF,OAF,OsteoclastActivatingFactor,Preinterleukin1beta,Preinterleukinbeta,ProInterleukin1beta)(FITC)
Pab
rabbit
rat
IgG
Rt
FITC
$592
E,WB
100ul
303592-FITC
Anti-SerumAmyloidP(9.5Salpha1Glycoprotein,9.5Salpha-1-glycoprotein,AmyloidPComponentSerum,APCS,PentaxinRelated,Pentraxin2,PTX2,PTX2,SAMP_HUMAN,SAP,SerumAmyloidPComponent,SerumAmyloidP-component(1-203))(FITC)
Pab
rabbit
rat
IgG
Rt
FITC
$592
IHC,WB
100ul
144120-HRP
Anti-Actin(Gamma-actin)(HRP)
Pab
rabbit
human
IgG
Hu,Mo,Rt
HRP
$628
ACTG1
IHC,WB
100ul
144129-HRP
Anti-ADAMTS2(ProcollagenIN-proteinase)(HRP)
Pab
rabbit
human
IgG
Hu,Rt
HRP
$628
ADAMTS2
IHC,WB
100ul
144160-HRP
Anti-ANGPTL3(ANG-5,ANGPT5,Angiopoietin-5)(HRP)
Pab
rabbit
human
IgG
Hu,Mo,Rt
HRP
$628
ANGPTL3
WB
100ul
144183-HRP
Anti-ApoptosisregulatorBcl-2(HRP)
Pab
rabbit
human
IgG
Hu
HRP
$592
BCL2
E,IP,N,WB
100ul
144190-HRP
Anti-AQP3(Aquaglyceroporin-3)(HRP)
Pab
rabbit
human
IgG
Hu,Mo,Rt
HRP
$628
AQP3
IC,IHC,WB
100ul