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蚂蚁淘在线 / 品牌中心 / Usbio / Usbio/ABL1, Recombinant, Human, His-Tag (ABL, JTK7, p150, c-ABL, v-abl, bcr/abl)/10ug/499759
商品描述
ABL1protooncogeneencodesacytoplasmicandnuclearproteintyrosinekinasethathasbeenimplicatedinprocessesofcelldifferentiation,celldivision,celladhesion,andstressresponse.ActivityofABLproteinisnegativelyregulatedbyitsSH3domainanddeletionoftheSH3domainturnsABL1intoanoncogene.Translocationandhead-to-tailfusionoftheBCRandABL1genesispresentinmanycasesofchronicmyelogeneousleukemia.TheDNA-bindingactivityoftheubiquitouslyexpressedABL1tyrosinekinaseisregulatedbyCDK1-mediatedphosphorylation,suggestingacellcyclefunctionforABL1.||Source:|RecombinantproteincorrespondingtohumanABL1,fusedtoHis-TagatN-terminal,expressedinInsectcells.||MolecularWeight:|~135kD||SpecificActivity:|871nmol/min/mgasperactivityassayprotocol.||Endotoxin:|<1EU/ug(LAL)||StorageandStABIlity:|Aliquottoavoidrepeatedfreezingandthawingandstoreat-70°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Source:Recombinant,Insectcells|Purity:Purified(~70-90%)|Concentration:Asreported|Form:Suppliedasaliquidin50mMsodiumphosphate,pH7.0,300mMsodiumchloride,150mMimidazole,0.1mMPMSF,0.2mMDTT,25%glycerol.||ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplicationswithouttheexpressedwrittenauthorizationofUnitedStatesBIOLOGical.
2018年8月,蚂蚁淘成为UnitedStatesBiological(简称USBio)代理商,UnitedStatesBiological也简称为USBiological。
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