GPNMB, also known as glycoprotein nmb, is a transmembrane glycoprotein that is expressed in numerous cells, including osteoclasts, macrophages, dendritic cells, and tumor cells. It shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. This protein participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. It may be involved in growth delay and reduction of metastatic potential. ||Source:|Recombinant protein corresponding to aa22-474 from human GPNMB, fused to His-Tag at C-terminal, expressed in insect cell.||Molecular Weight: |~51.8kD (462aa), 50-70kD (SDS-PAGE under reducing conditions.)||Endotoxin: |<1EU/1ug (determined by LAL method)||AA Sequence:|ADPAKRFHDV LGNERPSAYM REHNQLNGWS SDENDWNEKL YPVWKRGDMR WKNSWKGGRV QAVLTSDSPA LVGSNITFAV NLIFPRCQKE DANGNIVYEK NCRNEAGLSA DPYVYNWTAW SEDSDGENGT GQSHHNVFPD GKPFPHHPGW RRWNFIYVFH TLGQYFQKLG RCSVRVSVNT ANVTLGPQLM EVTVYRRHGR AYVPIAQVKD VYVVTDQIPV FVTMFQKNDR NSSDETFLKD LPIMFDVLIH DPSHFLNYST INYKWSFGDN TGLFVSTNHT VNHTYVLNGT FSLNLTVKAA APGPCPPPPP PPRPSKPTPS LGPAGDNPLE LSRIPDENCQ INRYGHFQAT ITIVEGILEV NIIQMTDVLM PVPWPESSLI DFVVTCQGSI PTEVCTIISD PTCEITQNTV CSPVDVDEMC LLTVRRTFNG SGTYCVNLTL GDDTSLALTS TLISVPHHHH HH||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 2018年8月，蚂蚁淘成为UnitedStatesBiological（简称USBio）代理商，UnitedStatesBiological也简称为USBiological。 欢迎广大客户咨询订货，在线QQ：3507623898 4000-520-616 最主要的一抗产品： 144747-FITC Anti-IL-6(BCellstimulatoryfactor2)(FITC) Pab rabbit human IgG Hu FITC $592 IL6 WB 100ul 144764-FITC Anti-Interferongamma(IFN-gamma)(FITC) Pab rabbit rat IgG Rt FITC $592 IFNG E,IHC,IP,N,WB 100ul 144739-FITC Anti-IL-3(Hematopoieticgrowthfactor,Mastcellgrowthfactor)(FITC) Pab rabbit human IgG Hu FITC $592 IL3 E,IHC,IP,N,WB 100ul 144964-FITC Anti-NFKB1(KBF1,NF-kappaB,NFkappaB,NF-kB1,NFKB-p50,EBP-1,p50,p105,TRANSCRIPTIONFACTORNFKB1,DNA-bindingfactorKBF1,NFKBp50,INCLUDED,NFKBp105,INCLUDED,NuclearfactorofkappalightpolypeptidegeneenhancerinBCells1)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 NFKB1 WB 100ul 303092-FITC Anti-ACE(ACE1,ACET,ACE_HUMAN,ACE1,AngiotensinConvertingEnzymeSomaticIsoform,AngiotensinConvertingEnzymeTestisSpecificIsoform,AngiotensinIConvertingEnzyme,AngiotensinIConvertingEnzyme1,AngiotensinIConvertingEnzymePeptidylDipeptidaseA1,Angiotensin-convertingEnzyme,Carboxycathepsin,CD143,CD143,CD143Antigen,DCP1,DCP,DCP1,DipeptidylCarboxypeptidase1,DipeptidylCarboxypeptidaseI,KininaseII,MVCD3,PeptidaseP,PeptidylDipeptidaseA,SolubleForm,TesticularECA)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $592 IHC,WB 100ul 145142-FITC Anti-SCF(Mastcellgrowthfactor)(FITC) Pab rabbit human IgG Hu FITC $592 KITLG E,WB 100ul 145147-FITC Anti-SDHA(FlavoproteinsubunitofcomplexII)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 SDHA IHC,WB 100ul 145286-FITC Anti-TNC(Hxb,Hexabrachion,Tenascin-C,TN-C,TN,CYTOTACTIN,hexabrachion(tenascinC,cytotactin),hexabrachion(tenascin),MGC167029)(FITC) Pab rabbit human IgG Hu,Mo,Rt FITC $628 TNC IHC,WB 100ul 303394-FITC Anti-Interleukin1Beta(IL1beta,Catabolin,H1,Hematopoietin1,IFNbetaInducingFactor,IL1,IL1beta,IL1B,IL-1beta,IL1Beta,IL1B,IL1B_HUMAN,IL1F2,Interleukin1betaPrecursor,Interleukin-1beta,LAF,OAF,OsteoclastActivatingFactor,Preinterleukin1beta,Preinterleukinbeta,ProInterleukin1beta)(FITC) Pab rabbit rat IgG Rt FITC $592 E,WB 100ul 303592-FITC Anti-SerumAmyloidP(9.5Salpha1Glycoprotein,9.5Salpha-1-glycoprotein,AmyloidPComponentSerum,APCS,PentaxinRelated,Pentraxin2,PTX2,PTX2,SAMP_HUMAN,SAP,SerumAmyloidPComponent,SerumAmyloidP-component(1-203))(FITC) Pab rabbit rat IgG Rt FITC $592 IHC,WB 100ul 144120-HRP Anti-Actin(Gamma-actin)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 ACTG1 IHC,WB 100ul 144129-HRP Anti-ADAMTS2(ProcollagenIN-proteinase)(HRP) Pab rabbit human IgG Hu,Rt HRP $628 ADAMTS2 IHC,WB 100ul 144160-HRP Anti-ANGPTL3(ANG-5,ANGPT5,Angiopoietin-5)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 ANGPTL3 WB 100ul 144183-HRP Anti-ApoptosisregulatorBcl-2(HRP) Pab rabbit human IgG Hu HRP $592 BCL2 E,IP,N,WB 100ul 144190-HRP Anti-AQP3(Aquaglyceroporin-3)(HRP) Pab rabbit human IgG Hu,Mo,Rt HRP $628 AQP3 IC,IHC,WB 100ul