- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
PI3K(p55gamma)alsoknownasPI3Kregulatorysubunit3(PIK3R3)wasfirstidentifiedby2-hybridsystemasaproteinthatbindtotheintracellulardomainofIGF1R.PIK3R3contains2Srchomology-2(SH2)domains,aninter-SH2/p110-bindingsiteandaproline-richmotif.PIK3R3transcriptisdetectedinallfetalandadulttissuesexceptperipheralbloodleukocytes.Expressionislowinadultliverandmostabundantinadulttestis.PIK3R3canbindIGF1R,INSR,andINSRsubstrate-1invitroandthebindingrequiresreceptoractivation(1).
GeneAliases:
PIK3R3,p55,p55-GAMMA,FLJ41892,DKFZp686P05226
GenbankNumber:
BC021622
References:
1.Dey,BR.etal:Cloningofhumanp55-gamma,aregulatorysubunitofphosphatidylinositol3-kinase,byayeasttwo-hybridlibraryscreenwiththeinsulin-likegrowthfactor-Ireceptor.Gene209:175-183,1998.