品牌分类
- 细胞因子
- Dihydropyrimidinase and Proteins
- Regulatory proteins
- 授予称号
- Peptide Substrates
- Isoform Specific Antibodies
- Deacetylase & Demethylase Proteins
- Acetyl & Methyltransferase Proteins
- siRNA Controls
- Cell Stress and Chaperone Proteins
- 激酶
- 双加氧酶与蛋白质
- Transcription Proteins
- Carbohydrate Kinases
- 表观遗传酶抑制剂
- Growth Factors
- 脂类激酶
- Phospholipase C and Proteins
- Mutant Kinases
- Oligo Substrates
- Fluorescent and Color Proteins
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商品描述
Overview:
VASPorVasodilator-stimulatedphosphoproteinisamemberoftheEna-VASPproteinfamilywhichcontainsanEHV1N-terminaldomainthatbindsproteinscontainingE/DFPPPPXD/EmotifsandtargetsEna-VASPproteinstofocaladhesions(1).VASPalsocontainsproline-richdomainthatbindSH3andWWdomain-containingproteins.VASPisassociatedwithfilamentousactinformationandlikelyplaysakeyroleincelladhesionandmotility.VASPisalsoinvolvedintheintracellularsignalingpathwaysthatregulateintegrin-extracellularmatrixinteractions.VASPisregulatedbythecyclicnucleotide-dependentkinasesPKAandPKG.
References:
1.Brindle,NPJ.etal:Thefocal-adhesionvasodilator-stimulatedphosphoprotein(VASP)bindstotheproline-richdomaininvinculin.Biochem.J.318753-757,1996.
