品牌分类
- 细胞因子
- Dihydropyrimidinase and Proteins
- Regulatory proteins
- 授予称号
- Peptide Substrates
- Isoform Specific Antibodies
- Deacetylase & Demethylase Proteins
- Acetyl & Methyltransferase Proteins
- siRNA Controls
- Cell Stress and Chaperone Proteins
- 激酶
- 双加氧酶与蛋白质
- Transcription Proteins
- Carbohydrate Kinases
- 表观遗传酶抑制剂
- Growth Factors
- 脂类激酶
- Phospholipase C and Proteins
- Mutant Kinases
- Oligo Substrates
- Fluorescent and Color Proteins
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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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商品描述
Overview:
EPHB2isamemberoftheEphfamilyofreceptortyrosinekinasesthatmediateneuro-developmentalprocessessuchasboundaryformation,axonguidance,vasculogenesisandcellmigration.ActivatedEPHB2regulatestheactivityofthenon-receptortyrosinekinaseAbl(1).EPHB2isoverexpressedinanumberoftumors,particularlyglioblastoma.Infact,EPHB2overexpressionleadstoincreasedgliomacellmigrationandinvasion(2).
References:
1.Yu,HH.etal:MultiplesignalinginterationofAblandArgkinaseswiththeEPhB2receptor.Oncogene.2001Jul5;20(30):3995-4006.2.Nakada,M.etal:ThephosphorylationofEphB2receptorregulatesmigrationandinvasionofhumangliomacells.CancerRes.2004May1;64(9):3179-85.
