- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
CDK3/CyclinE1isamemberofthecyclin-dependentproteinkinasefamilyandpromotesentryintoSphase,inpartbyactivatingmembersoftheE2Ffamilyoftranscriptionfactors.CDK3canalsoassociatewithcyclinCandphosphorylatestheretinoblastoma1proteintopromoteexitfromG0.TheCDK3genehasbeenmappedtochromosomallocationof17q22-qter,telomerictotheBRCA1genebysomaticcellhybridsanalysis(1).ThepresenceofasinglepointmutationintheCDK3genefromseveralMusmusculusstrainscommonlyusedinthelaboratoryhasbeenreported(2).
GeneAliases:
CDK3:NoneCyclinE1:CCNE1,CCNE
GenbankNumber:
NM_001258NM_001238
References:
1.Bullrich,F.etal:Chromosomalmappingofmembersofthecdc2familyofproteinkinases,cdk3,cdk6,PISSLRE,andPITALRE,andacdkinhibitor,p27-Kip1,toregionsinvolvedinhumancancer.CancerRes.55:1199-1205,1995.2.Ye,X.etal:Apremature-terminationmutationintheMusmusculuscyclin-dependentkinase3gene.Proc.Nat.Acad.Sci.98:1682-1686,2001.
