- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
Overview:
GRK3orbeta-adrenergicreceptorkinase2specificallyphosphorylatestheagoNIST-occupiedformofthebeta-adrenergicandrelatedGprotein-coupledreceptors.GRK3isamemberofthereceptorkinasefamilythatbroadlyservestoregulatereceptorfunction(1).GRK3has85%aminoacidsimilaritywithbetaadrenergicreceptorkinase1,withtheproteinkinasecatalyticdomainhaving95%similarity.GRK3ishighlyexpressedinlung,heart,andADIposetissue(2).Singlenucleotidepolymorphisms(SNPs)inthepromoterregionofGRK3havebeenassociatedwithbipolardisorder.
GeneAliases:
ADRBK2;BARK2
GenbankNumber:
NM_005160
References:
1.Benovic,J.L.et.al:Cloning,expression,andchromosomallocalizationofbeta-adrenergicreceptorkinase2:anewmemberofthereceptorkinasefamily.J.Biol.Chem.266:14939-14946,1991.2.Parruti,G.et.al:Molecularcloning,functionalexpressionandmRNAanalysisofhumanbeta-adrenergicreceptorkinase2.Biochem.Biophys.Res.Commun.190:475-481,1993.
