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Description
PepJetDNAInVivoTranfectionReagentisanovelcationicpeptidebasedDNAdeliverytool.This28amino-acidslongpeptideisaccidentllyidentifiedasastrongvectorindeliveringDNAinvivo.Withhelpofproteinalignmentandsimulationsoftware,thepeptidewassynthesized,refined,screenedandvalidatedbysimulatingavirusprotein.AshieldpeptidewasalsolinkedtothebackbonetopreventInVivoenvironmentinterferences,leADIngtohighInVivotransfectionefficiency.PepJetwasconfirmedtogivebestrenillaluciferaseexpressioninlung,liver,spleenandkidney.
StorageCondition
Storeat4°C.Ifstoredproperly,theproductisstablefor12monthsorlonger.
ComparisonofthedeliveryefficienciestodifferentorgansinmiceofaplasmidcontainingtheRenillaluciferasegenemediatedbyPepJetreagent.
DataSheet