AdenovirusAmplificationServiceLargeScaleProductionofRecombinantSEROtype5Adenovirus(E1/E3deletion)withAd.MAXSystem:
-Unsurpassabletransductionefficiency(nearly100%vs.AAV30~40%andLentivirus~30%)inmostmammaliancells.
-Nointegrationintohostgenome.
-CompatIBLewithtoxicgeneofinterest(GOI).
-Inducehigh-leveltransientproteinexpression.
-Accommodateinsertsofupto7.5kb.
ServiceDescription:
1.Generationofhightiterrecombinantadenoviralstocksin~4000cm2ofAd.MAX™293cells.
2.2xCsClultracentrifugeforhighlypurifiedadenovirus.
3.AdenovirusPFUtitration.
RequiredMaterials:Customerprovideadenovirusvectororselectourpre-packagedadenovirusvectors.
TurnaroundTime:1~2weeks.
Deliverables:>2.0mL(10x0.2mL)superpurifiedinvivogradeofadenovirusparticlesat>5E+10~5E+11PFU/mL*.
Weofferdiscountfornewcustomers,pleaserequestaquotewithustoday.
*Finaladenovirusyieldmaydependonthenatureoftransgene.
Signagen腺伴随病毒(AAV)是一种小型(直径20 nm)的复制缺陷型无包膜病毒,可感染人类和其他灵长类动物。目前尚不知道AAV会引起疾病,因此该病毒会引起非常轻微的免疫反应。AAV可以感染分裂细胞和非分裂细胞,并且可以将其基因组整合到宿主细胞的基因组中。