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Novus/Imiquimod, TLR7 ligand/NBP2-26228-1mg

价格
¥1980.00
货号:NBP2-26228-1mg
浏览量:127
品牌:Novus
服务
全国联保
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商品描述
Description
Imiquimod, TLR7 ligand is an imidazoquinoline amine analog to guanosine. As a synthetic molecule of the Imidazoquinoline family, it has potent immunostimulatory activity. Imiquimod has been shown to activate only TLR7. This activation is MyD88 dependant and leads to the induction of the transcription factor NF-kB.
Specificity
Imiquimod is human/mouse TLR7 agonist.
Endotoxin Note
<0.001>
Application Notes
Formula: C14H16N4, HCl.Molecular weight: 276.8. This product is useful for activation of TLR7 and stimulation of TLR7 has been achieved with 5-10 ug/mL. Use in ligand activation, functional, and in vitro assays reported in scientific literature (PMID 25957979)
Reviewed Applications
Read 2 Reviews rated 5
using NBP2-26228 in the following application:
  • Immunocytochemistry/Immunofluorescence
  • Serum
Publications
ReadPublications using NBP2-26228 in the following applications:
  • Flow-IC
    1 publication
  • Func
    4 publications
  • In vitro
    3 publications
  • In vivo
    1 publication
  • LA
    1 publication
  • in-vitro
    1 publication
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