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商品描述
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x1h,1x10min. |
| Standardrange | 0.08-5ng/ml |
| Specimen/Volumes | 20µlserum,50µlplasma |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:CD40LHighSensitivityELISA
IBL我们的液体处理专业知识可实现高度复杂的分子诊断技术的可靠自动化，例如细胞遗传学（核型分析和FISH）和分子细胞遗传学（aCGH /阵列比较基因组杂交），其应用范围从代谢疾病和癌症到生殖遗传学和移植药物。该产品组合涵盖了细胞遗传学和分子细胞遗传学工作流程的关键阶段，从标准化工作站，经过验证的应用程序和专用用户界面，到与Tecan Labwerx合作开发的高度定制的平台。 ThisHighSensitivityELISAenablestheanalysisofTNF-alphainlowconcentrationsfromserum,plasma,orcellculturesamples.TheHighSensitivityELISAKitsofferaccuratequantificationbelowconventionalELISAlimits.
CD40belongstotheTNFreceptorsuperfamilyandisabiochemicalMarkerfortheidentificationofactivatedplateletsofpatientswithcardiovasculardiseases(anginapectoris,infarction,strokeetc.)
AkeyroleofCD40/CD40ligandinteractionsinimmuneactivation,particularlyinT-celldependentBcellresponsesisanticipated.CD40LigandisexpressedonthesurfaceofactivatedCD4+Tcells,basophils,andmastcells.BindingofCD40Ltoitsreceptor,CD40,onthesurfaceofBcellsstimulatesB-cellproliferation,adhesionanddifferentiation.AsolubleisoformofCD40Lhasbeenshowntoexistinthecirculation.Thissolublemoleculeisahomotrimerofa18kDaproteinexhibitingfullactivityinBcellproliferationanddifferentiationassays,isabletorescueBcellsfromapoptosisandbindssolubleCD40.
CD40LisdiscussedinrelationtoapotentialroleinsupportingBcelltumorsandithasbeendiscoveredthatthemoleculardefectintheX-linkedHyper-IgM-SyndromeistargetedtotheCD40Lgene,itisfunctionalinvolvedinBcellhybridomasandchroniclymphocyticleukemiaaswellasseveralautoimmunediseases.
Synonyms:CD40Ligand;TNFligandsuperfamilymember5;TNFrelatedactivationprotein;TcellantigenGp39;CD154antigen;hyperIgMsyndrome
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.CD40belongstotheTNFreceptorsuperfamilyandisabiochemicalMarkerfortheidentificationofactivatedplateletsofpatientswithcardiovasculardiseases(anginapectoris,infarction,strokeetc.)
AkeyroleofCD40/CD40ligandinteractionsinimmuneactivation,particularlyinT-celldependentBcellresponsesisanticipated.CD40LigandisexpressedonthesurfaceofactivatedCD4+Tcells,basophils,andmastcells.BindingofCD40Ltoitsreceptor,CD40,onthesurfaceofBcellsstimulatesB-cellproliferation,adhesionanddifferentiation.AsolubleisoformofCD40Lhasbeenshowntoexistinthecirculation.Thissolublemoleculeisahomotrimerofa18kDaproteinexhibitingfullactivityinBcellproliferationanddifferentiationassays,isabletorescueBcellsfromapoptosisandbindssolubleCD40.
CD40LisdiscussedinrelationtoapotentialroleinsupportingBcelltumorsandithasbeendiscoveredthatthemoleculardefectintheX-linkedHyper-IgM-SyndromeistargetedtotheCD40Lgene,itisfunctionalinvolvedinBcellhybridomasandchroniclymphocyticleukemiaaswellasseveralautoimmunediseases.
Synonyms:CD40Ligand;TNFligandsuperfamilymember5;TNFrelatedactivationprotein;TcellantigenGp39;CD154antigen;hyperIgMsyndrome
