Kitsize | 12x8 |
Method | ELISA |
Incubationtime | 3x1h,1x5min |
Standardrange | 1.56-100ng/mL |
Specimen/Volumes | 100µLstool,urine |
Substrate/isotope | TMB450nm |
RegulatoryStatus: | EU:CE |
Enzymeimmunoassayforthein-vitrodeterminationofMyeloperoxidase(MPO)inhumanurineandstool.
Thegranulesofneutrophils(approx.70%ofthewhitebloodcells)containalargenumberofdifferentenzymes.Myeloperoxidase(MPO)catalyzestheoxidationofsubstancesthroughH2O2.TheMPOH2O2–systemhasatoxiceffectonmanymicroorganismssuchasbacteria,fungi,virusesandmycoplasma.Theefficiencyofthebacteria-destructiveMyeloperoxidaseH2O2–systemisincreasedbyPMN-Elastase.MPOdeterminationinthe,stoolreflectstheinflammatoryactivityofCrohn´sdiseaseorulcerativecolitis.
Indication
- Markerforinflammatoryactivitiesinthegastrointestinaltract
- Renaltransplantrejection
- Oxidativestress
- Forthedifferentiationbetweenallergicandinfectiousasthma