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IBL/sPECAM-1 (monkey) ELISA/BE45751/

价格
面议
货号:BE45751
浏览量:122
品牌:IBL
服务
全国联保
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签订合同
商品描述
Kitsize12x8
MethodELISA
Incubationtime1x3h,1x10min
Standardrange0.48-30U/mL
Specimen/Volumes10µLserum,plasma,cellculturesupernatantetal.
Substrate/isotopeTMB450nm
RegulatoryStatus:Forresearchuseonly
Detailsfor: sPECAM-1(monkey)ELISA
PECAM-1isatransmembraneglycoproteinwithamolecularweightofapproximately130kDa,dependingonthedegreeofglycosylation.PECAM-1isconstitutivelyexpressedonallvascularcellsandhasprovidedausefulimmunohistochemicalMarkerofbloodvessels,particularlyinthesettingofangiogenesis.Ithasalsobeenfoundonplatelets,monocytes,neutrophilsandCD8+Tcells.BonemarrowstemcellsandtransformedcelllinesofthemyeloidandmegakaryocyticlineagealsoexpressPECAM-1.Interestingly,PECAM-1wasalsodetectedonhuman,mouseandratsolidtumorlines.RecentstudiessuggestaroleforPECAM-1intheinflammatoryprocessandleukocyte-endothelialinteraction.PECAM-1isanearlyandsensitivemarkerfortumor-inducedangiogenesis.SeveraldatahavesuggestedthatPECAM-1maybeinvolvedintheprocessofangiogenesisinadevelopingvertebrateembryoaswellasduringmetastasesformation.Besidesthemembrane-boundformofPECAM-1asolubleformofthemoleculeexists,whichis5-10kDasmallerthancell-associatedPECAM-1,andcontainsthecytoplasmictail.SolublePECAM-1wasdetectedinnormalhumanplasma.

Synonyms:Leukocytesurfaceprotein,CD31,EndoCAM,HEC7
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.
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