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商品描述
| Kitsize | 12x8 |
| Method | ELISA |
| Incubationtime | 1x2h,1x10min |
| Standardrange | 19-1250U/mL |
| Specimen/Volumes | 50µLserum,plasma,cellculturesupernatantetal. |
| Substrate/isotope | TMB450nm |
| RegulatoryStatus: | Forresearchuseonly |
Detailsfor:Interleukin-8/IL-8(monkey)ELISA
IBL我们的液体处理专业知识可实现高度复杂的分子诊断技术的可靠自动化，例如细胞遗传学（核型分析和FISH）和分子细胞遗传学（aCGH /阵列比较基因组杂交），其应用范围从代谢疾病和癌症到生殖遗传学和移植药物。该产品组合涵盖了细胞遗传学和分子细胞遗传学工作流程的关键阶段，从标准化工作站，经过验证的应用程序和专用用户界面，到与Tecan Labwerx合作开发的高度定制的平台。 Interleukin-8selectivelystimulatestheABIlityofneutrophilsandT-lymphocytestoinvadeinjuredorinflamedtissue.IL-8alsoknownasCXCL8thatispurifiedfromperipheralbloodmonocytesisa10kDaproteinshowingatleast4variantforms(77,72,70,and69aminoacids,respectively)whichdifferinthelengthoftheN-terminalandreADIlyformdimersinsolution.Twocystin-bridgesareessentialfortheBIOLOGicalactivityofIL-8.ExogenousstimulilikeLPS,butalsoIL-1,TNF-alphaandTNF-betainducethesecretionofIL-8inavarietyofdifferentcelltypesincludingmonocytes,endothelialandepithelialcells,peripheralbloodmononuclearcells,dermalfibroblasts,keratinocytes,neutrophils,hepatocytes,synovialcells,andT-lymphocytes.TheactivitiesofIL-8arenotspecies-specific.HumanIL-8isalsoactiveinrodentandrabbitcellsanddiffersfromallothercytokinesinitsabilitytospecificallyactivateneutrophilgranulocytes.Thischemokineactivatesmultipleintracellularsignalingpathwaysdownstreamoftwocell-surface,Gprotein-coupledreceptors(CXCR1andCXCR2).ThepropertyofIL-8tostimulatemovementofneutrophilsacrossendothelialmonolayersinvitrosupportstheconceptofacentralroleforthismoleculeintheaccumulationofneutrophilsatinflammatorylesionsinvivo.
Synonyms:Protein3-10C,CXCL8,NAP-1,GCP-1
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Synonyms:Protein3-10C,CXCL8,NAP-1,GCP-1
