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苏州工业园区生物纳米园A4#216
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4000-520-616 / 18915418616
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0512-67156496
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商品描述
| Kitsize | 12x8 |
| Method | LuminescenceImmunoassay |
| Incubationtime | 1x3h;1x10min |
| Standardrange | 0.015-3.20µg/dL |
| Specimen/Volumes | 20µLSaliva |
| Substrate/isotope | Luminol |
| RegulatoryStatus: | IVD,EU:CE |
Detailsfor:CortisolSalivaLuminescenceImmunoassay
IBL我们的液体处理专业知识可实现高度复杂的分子诊断技术的可靠自动化，例如细胞遗传学（核型分析和FISH）和分子细胞遗传学（aCGH /阵列比较基因组杂交），其应用范围从代谢疾病和癌症到生殖遗传学和移植药物。该产品组合涵盖了细胞遗传学和分子细胞遗传学工作流程的关键阶段，从标准化工作站，经过验证的应用程序和专用用户界面，到与Tecan Labwerx合作开发的高度定制的平台。 TheIBLInternationalCortisolSalivaLuminescenceImmunoassayisintendedforthein-vitro-diagnosticquantitativedeterminationofCortisolinhumansalivaandforuseasanaidinthediagnosisandtreatmentofadrenaldisorders.
Thisdeviceisnotintendedforpoint-of-caresettings.
Cortisol(alsoknownashydrocortisone,compoundF)isthemainglucocorticoidinhumansandisproducedinthezonafasciculataoftheadrenalcortex.90%ofthecirculatingcortisolareboundtocorticoidbindingglobulin(CBG,Transcortin),ca.7%areboundtoalbuminandonly1–3%areunbound.Onlythelatterpartrepresentstheactiveformofcortisol.Thefreecortisolisreleasedinsalivaandisexcretedviathekidneysasasmallpartamongthemetabolitesofcortisol.TheleveloffreecortisolinbloodregulatesmainlyitssecretionintheadrenalcortexinanegativefeedbackmechanismviaCRH(corticotropinreleasinghormone)inthehypothalamicregionandtheACTHinthepituitarygland,butitisalsoaffectedbydifferentsituationsaboveallbystress.
Inhumansthereisaphysiologicalfluctuationofcortisolachievingthehighestlevelinthemorningandthelowestduringmidnight.Thisfluctuationofcortisolplasmalevelisreflectedinsalivanormallywithapeakinthefirst90minutesafterwakeup.Thecortisolmeasurementisindicatedinadrenaldisorders.Duetothediurnalfluctuationsofcortisolasalivarysamplecollectionisaneasymethodwithoutthestressofrepeatedvenipunctures.
OurNewIBLCortisolSalivaLuminescenceImmunoassayiscalibratedtothereferencemethodoftheLC-MS/MSandreplacestheformerproductreferencedRE62011.Pleasecontactusifyoushouldrequireanyspecificinformation!
TheLuminescenceIAisalsoavailableinbulkformat(10x96tests),withthecataloguenumberRE62119.
ForconcretedatapleaseconsulttheInstructionforUseinthedownloadboxontherightside.Thisdeviceisnotintendedforpoint-of-caresettings.
Cortisol(alsoknownashydrocortisone,compoundF)isthemainglucocorticoidinhumansandisproducedinthezonafasciculataoftheadrenalcortex.90%ofthecirculatingcortisolareboundtocorticoidbindingglobulin(CBG,Transcortin),ca.7%areboundtoalbuminandonly1–3%areunbound.Onlythelatterpartrepresentstheactiveformofcortisol.Thefreecortisolisreleasedinsalivaandisexcretedviathekidneysasasmallpartamongthemetabolitesofcortisol.TheleveloffreecortisolinbloodregulatesmainlyitssecretionintheadrenalcortexinanegativefeedbackmechanismviaCRH(corticotropinreleasinghormone)inthehypothalamicregionandtheACTHinthepituitarygland,butitisalsoaffectedbydifferentsituationsaboveallbystress.
Inhumansthereisaphysiologicalfluctuationofcortisolachievingthehighestlevelinthemorningandthelowestduringmidnight.Thisfluctuationofcortisolplasmalevelisreflectedinsalivanormallywithapeakinthefirst90minutesafterwakeup.Thecortisolmeasurementisindicatedinadrenaldisorders.Duetothediurnalfluctuationsofcortisolasalivarysamplecollectionisaneasymethodwithoutthestressofrepeatedvenipunctures.
OurNewIBLCortisolSalivaLuminescenceImmunoassayiscalibratedtothereferencemethodoftheLC-MS/MSandreplacestheformerproductreferencedRE62011.Pleasecontactusifyoushouldrequireanyspecificinformation!
TheLuminescenceIAisalsoavailableinbulkformat(10x96tests),withthecataloguenumberRE62119.
