Discovery蚂蚁淘在线

商品

品牌

文章

热门搜索：

快报

蚂蚁淘特色产品FLOWTECH造影剂蚂蚁淘授权代理品牌-德国Emfret 蚂蚁淘旗下188精品现货平台正式上线啦！！！蚂蚁淘四月促销蚂蚁淘获得vitanavitech代理商授权蚂蚁淘获得QA-bio代理商授权蚂蚁淘获得Viagenbiotech代理商授权 polysciences公司24765-1到现货了(内附代理商整理说明书）蚂蚁淘四月团建“环苏州古城一周” Clodronate Liposomes用量更正！

品牌首页品牌新闻品牌简介产品中心品牌咨询联系我们

品牌咨询

联系方式

公司地址

苏州工业园区生物纳米园A4#216

联系电话

4000-520-616 / 18915418616

传真号码

0512-67156496

电子邮箱

info@ebiomall.com

公司网址

https://www.ebiomall.com

蚂蚁淘在线 / 品牌中心 / Discovery / Discovery Antibodies/Anti-GluR1 (GluA1) (extracellular) Antibody/0.2 ml/AGC-004-0.2 ml

Discovery Antibodies/Anti-GluR1 (GluA1) (extracellular) Antibody/0.2 ml/AGC-004-0.2 ml

价格

￥9500.00

货号：AGC-004-0.2ml

浏览量：100

品牌：Discovery

服务

全国联保

正品保证

正规发票

签订合同

加入收藏

立即购买

商品描述

Cat#:AGC-004

AlternativeNameAMPAReceptor1,Glutamatereceptor1,Ionotropicglutamatereceptor1,AMPA-selectiveglutamatereceptor1,GRIA1, GluR-A, GluR-K1

KOValidated

LyophilizedPowder

AntigenIncl.

Type:Polyclonal

Host:Rabbit

Reactivity:h,m,r

Immunogen-+

Accession(Uniprot)NumberP19490

GeneID50592

PeptideconfirmationConfirmedbyaminoacidanalysisandmassspectrometry.

HomologyMouse-14/15amino acidresiduesidentical;human-12/15aminoacidresiduesidentical.

RRIDAB_2039878.

PurityAffinitypurifiedonimmobilizedantigen.

FormLyophilizedpowder.Reconstitutedantibodycontainsphosphatebufferedsaline(PBS),pH7.4,1%BSA,0.05%NaN₃.

IsotypeRabbitIgG.

StoragebeforereconstitutionTheantibodyshipsasalyophilizedpowderatroomtemperature.Uponarrival,itshouldbestoredat-20°C.

Reconstitution25μl,50μlor0.2mldoubledistilledwater(DDW),dependingonthesamplesize.

Antibodyconcentrationafterreconstitution0.8mg/ml.

StorageafterreconstitutionThereconstitutedsolutioncanbestoredat4°Cforupto1week.Forlongerperiods,smallaliquotsshouldbestoredat-20°C.Avoidmultiplefreezingandthawing.Centrifugeallantibodypreparationsbeforeuse(10000xg5min).

NegativecontrolantigenstoragebeforereconstitutionLyophilizedpowdercanbestoredintactatroomtemperaturefor2weeks.Forlongerperiods,itshouldbestoredat-20°C.

Negativecontrolantigenreconstitution100µldoubledistilledwater(DDW).

Negativecontrolantigenstorageafterreconstitution-20°C.

PreadsorptionControl1μgpeptideper1μgantibody.

StandardqualitycontrolofeachlotWesternblotanalysis.

Applications:ic,if,ih,lci,wb

Mayalsoworkin:ifc*,ip*

Westernblot-+

Immunohistochemistry-+

Livecellimaging/Immunocytochemistry-+

References

1.Dingledine,R.etal.(1999)Pharmacol.Rev.51,7.

2.Sheng,M.andLee,S.H.(2001)Cell105,825.

3.Song,I.andHuganir,R.L.(2002)TrendsNeurosci.25,578.

Scientificbackground-+

LyophilizedPowderNegativeControlAntigenIncluded

Clickheretoreceivea25µlfreetrialsample!

Lastupdate:14/01/2020

Anti-GluR1(GluA1)(extracellular)Antibody(#AGC-004)isahighlyspecific antibodydirectedagainstanextracellularepitopeoftherationotropicglutamatereceptor1.Theantibody canbeusedinwesternblot,immunohistochemistry,immunocytochemistry,andlivecellimagingapplications.IthasbeendesignedtorecognizeGluR1fromhuman,mouse,andratsamples.

Forresearchpurposesonly,notforhumanuse

Discovery Antibodies的Cyclin dependant kinase 2 (CDK2) is a serine/threonine protein kinase which controls both G1/S and G2/M transitions. CDKs along with cyclins and CDK inhibitors regulate cell cycle progression. Specific cyclins activate different CDKs; in early G1, CDK2 pairs with cyclin E to promote entry into the S phase before switching to partner with cyclin A to drive the cell through S phase. Once activated CDKs phosphorylate downstream proteins to initiate signalling cascades. CDK2 phosphorylates and inactivates the RB1 (pRb) tumour suppressor family of proteins.CDK的活动受到严格控制。CDK2活性可以被包括P21在内的一系列抑制剂抑制。细胞周期失调和增殖控制的丧失与细胞转化和癌症密切相关。CDK2在DNA损伤反应（DDR）中的细胞周期停滞中也似乎起着积极作用，它的抑制作用会阻碍DDR，并使细胞对电离辐射敏感，从而诱导细胞死亡。该抗体与AlexaFluor®488偶联。AlexaFluor®488是一种流行的鲜绿色荧光染料，具有高pH稳定性。

资质认证

获得国家资质，权威认证！
全国联保

全国联保，官方无忧售后
正规发票

正规发票，放心购买
签订合同

签订合同，保障您的权益

/**/

Discovery Antibodies/Anti-GluR1 (GluA1) (extracellular) Antibody/0.2 ml/AGC-004-0.2 ml

Applicationkey:

Speciesreactivitykey: