| Catalogue number | crb2115009e |
|---|---|
| Antibody | crb2115009e Alexa Fluor® 488 Anti-Glutamate Transporter (GLAST) antibodyAnti-GLAST Antibody |
| Antigen Peptide | KLH conjugated synthetic peptide crb1200276e |
| Protein ID | UniProtKB - P24942 |
| Aliases | SLC1A3, Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, GLAST GLutamate ASpartate Transporter, EAAT1 Excitatory Amino Acid Transporter 1 |
| Cross-Reactivity | Rat, Mouse |
| Host Species | Anti-Rabbit |
| Antibody Type | Polyclonal |
| Label | Labelled with Alexa Fluor® 488 under optimal conditions. Ex: 495nm Em:519nm |
| Concentration | 0.56mg/ml |
| Validation | ELISA |
| Target | GLAST |
| Disease Area | Neurodegenerative diseases |
| Family | sodium:dicarboxylate (SDF) symporterfamily. |
| Specificity | Protein |
| Storage | Supplied in PBS containing 0.01% sodium azide. The product should be stored undiluted and protected from prolonged exposure to light. Short term storage between 2-8°C and long term storage below -20°C |
| References | Martin, C., Houitte, D., Guillermier, M., Petit, F., Bonvento, G. and Gurden, H. (2012). Alteration of sensory-evoked metabolic and oscillatory activities in the olfactory bulb of GLAST-deficient mice. Front Neural Circuits, 6. PMID: 22291618 Perkins, E., Clarkson, Y., Suminaite, D., Lyndon, A., Tanaka, K., Rothstein, J., Skehel, P., Wyllie, D. and Jackson, M. (2018). Loss of cerebellar glutamate transporters EAAT4 and GLAST differentially affects the spontaneous firing pattern and survival of Purkinje cells. Hum Mol Genet, 27(15), 2614-2627. PMID: 29741614 Siddiqi, F., Chen, F., Aron, A., Fiondella, C., Patel, K. and LoTurco, J. (2012). Fate Mapping by PiggyBac Transposase Reveals That Neocortical GLAST+ Progenitors Generate More Astrocytes Than Nestin+ Progenitors in Rat Neocortex. Cereb Cortex, 24(2), 508-520. PMID: 23118195 |
