AG Scientific/Kendomycin/K-2015/0.5 mg

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¥5655.60
货号:K-2015-0.5mg
浏览量:116
品牌:AG Scientific
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商品描述

*Please inquire the availability for this product. Kendomycin is an unusual macrocyclic metabolite containing a rare quinone methide group. Kendomycin is a potent antibacterial agent against Gram positive and Gram negative bacteria, including MRSA strains, also displaying antitumor activity. Kendomycin is a potent endothelin receptor antagonist and demonstrates antiosteoporotic activity.

Additional Information

SynonymsTAN 2162
Product #K-2015
CAS #183202-73-5
FormulaC29H42O6
MW486.6
AppearanceYellow solid
Purity>95% by HPLC
SolubilitySoluble in DMSO, and methanol
Melting Point270.93 °C
Boiling Point678.49 °C at 760 mmHg
Storage Temp-20°C
Therapeutic AreaOrthopedic Disorders
UseKendomycin is a polyketide macrolide antibiotic isolated from various Streptomyces strains, with demonstrated cytotoxic and antiosteoporotic properties

Additional Information

MDL NumberMFCD14635192
InChIInChI=1S/C29H42O6/c1-14-8-9-22-18(5)24(30)19(6)28(34-22)23-21-13-29(33,17(4)12-16(3)11-15(2)10-14)35-27(21)20(7)25(31)26(23)32/h10,13-14,16-19,22,24,28,30,32-33H,8-9,11-12H2,1-7H3/b15-10+/t14-,16+,17-,18-,19+,22+,24-,28+,29+/m0/s1
SMILESC[C@H]1CC[C@@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C3=C(C(=O)C(=C4C3=C[C@@](O4)([C@H](C[C@@H](C/C(=C1)/C)C)C)O)C)O)C)O)C
盐酸贝斯他汀的应用:•急性早幼粒细胞白血病的治疗•增强了低剂量NA3的抗伤害作用•增强骨髓巨噬细胞祖细胞的增殖•增强CFU-GM菌落的形成•肺癌治疗的疗效