AG Scientific/Echinocandin B/E-2415/1 mg

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¥6402.60
货号:E-2415-1mg
浏览量:107
品牌:AG Scientific
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商品描述
*PleaseinquiretheavailABIlityforthisproduct.EchinocandinBisthemajoranalogueofafamilyoflipopeptidesisolatedfromseveralspeciesofAspergillus,reportedin1974.EchinocandinBisapotentantifungalandactsbyinhibitingthesynthesisofβ-(1,3)-D-glucan,anessentialcomponentofthecellwallofsusceptIBLefungi.

AdditionalInformation

AdditionalInformation

SynonymsA30912,A22082,7810,SL7810F
Product#E-2415
CAS#54651-05-7
FormulaC52H81N7O16
MW1060.4
AppearanceOffwhitetobrownishpowder
Purity>95%byHPLC
SolubilitySolubleinethanol,methanol,DMSO,DMFLimitedwatersolubility
BoilingPoint1383.99°Cat760mmHg
StorageTemp-20°C
TherapeuticAreaInfectiousDiseases
UseAntifungalagentswhichinhibitsthesynthesisofglucan,amajorcomponentofthefungalcellwall,vianoncompetitiveinhibitionofacrucialenzyme,β-(1,3)-D-glucansynthase
盐酸贝斯他汀的应用:•急性早幼粒细胞白血病的治疗•增强了低剂量NA3的抗伤害作用•增强骨髓巨噬细胞祖细胞的增殖•增强CFU-GM菌落的形成•肺癌治疗的疗效
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MDLNumberMFCD03265632
InChIInChI=1S/C52H81N7O16/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-38(65)53-35-26-37(64)48(71)57-50(73)42-43(66)29(2)27-59(42)52(75)40(31(4)61)55-49(72)41(45(68)44(67)32-21-23-33(62)24-22-32)56-47(70)36-25-34(63)28-58(36)51(74)39(30(3)60)54-46(35)69/h9-10,12-13,21-24,29-31,34-37,39-45,48,60-64,66-68,71H,5-8,11,14-20,25-28H2,1-4H3,(H,53,65)(H,54,69)(H,55,72)(H,56,70)(H,57,73)/b10-9-,13-12-/t29-,30-,31-,34+,35-,36-,37+,39-,40-,41-,42-,43-,44-,45-,48+/m0/s1
SMILESCCCCC/C=CC/C=CCCCCCCCC(=O)N[C@H]1C[C@H]([C@H](NC(=O)[C@@H]2[C@H]([C@H](CN2C(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@@H](NC1=O)[C@H](C)O)O)[C@@H]([C@H](C4=CC=C(C=C4)O)O)O)[C@H](C)O)C)O)O)O